Assoc. Prof. Dr. Shi-liang Huang | Tumor | Best Researcher Award

Assoc. Prof. Dr. Shi-liang Huang | Tumor | Best Researcher Award

Sun Yat-sen University | China

AUTHOR PROFILE

Scopus

ORCID ID

🧑‍🔬 DR. SHI-LIANG HUANG

Associate Professor in Medicinal Chemistry
Sun Yat-sen University, People’s Republic of China

🎯 OBJECTIVE

Dedicated Associate Professor specializing in Medicinal Chemistry, with a passion for driving innovation in drug discovery and development, focusing on the tumor microenvironment and the heat shock response.

📘 EARLY ACADEMIC PURSUITS

Dr. Huang’s academic journey began with a solid foundation in Chemistry and Biochemistry, laying the groundwork for a distinguished career. After excelling in undergraduate studies, Dr. Huang pursued advanced degrees in Medicinal Chemistry, demonstrating exceptional aptitude for research and innovation.

Key achievements during this phase include:

  • Master’s Thesis: Groundbreaking work on natural product derivatives for therapeutic applications.
  • Doctoral Research: Advanced studies on the mechanisms of small molecules in altering biochemical pathways.

🏢 PROFESSIONAL ENDEAVORS

As an Associate Professor at Sun Yat-sen University, Dr. Huang has significantly contributed to the university’s reputation as a leading institution in medicinal research. His professional journey is marked by:

  • Leading Interdisciplinary Teams: Collaborating with experts in oncology, biochemistry, and computational modeling.
  • Research Innovation: Pioneering techniques in synthesizing inhibitors targeting heat shock proteins (HSPs) and heat shock factor 1 (HSF1).
  • Teaching Excellence: Mentoring students in natural medicinal chemistry and drug design methodologies.

🧪 CONTRIBUTIONS AND RESEARCH FOCUS

Dr. Huang’s work revolves around integrating bioorganic chemistry with tumor microenvironment studies to innovate cancer therapies. Key contributions include:

  • Medicinal Chemistry: Developing novel molecules with high specificity for cancer-related targets.
  • Natural Product Exploration: Isolating and modifying natural compounds to enhance their therapeutic potential.
  • Heat Shock Response Modulation: Designing inhibitors to disrupt HSF1 and HSP pathways, which are critical in cancer cell survival under stress.
  • Tumor Microenvironment Studies: Investigating how microenvironmental factors influence drug efficacy.

🌟 IMPACT AND INFLUENCE

Dr. Huang’s research has had a profound impact on the scientific community and beyond:

  • Published Works: Author of numerous peer-reviewed articles in high-impact journals.
  • Citations and Recognition: Garnered widespread academic citations, reflecting the influence and applicability of his research.
  • Collaboration and Leadership: Actively involved in global collaborations, enhancing the translational impact of his findings.

📊 ACADEMIC CITATIONS AND METRICS

Dr. Huang’s academic metrics underscore his scholarly contributions:

  • H-Index: Demonstrates significant citation impact in medicinal chemistry and oncology.
  • Published Articles: Over 50 research papers, including breakthroughs in bioorganic and natural medicinal chemistry.
  • Research Grants: Secured funding for multiple national and international projects.

🏆 LEGACY AND FUTURE CONTRIBUTIONS

As a visionary in drug discovery, Dr. Huang aspires to expand his research impact by:

  • Advancing precision medicine approaches tailored to the tumor microenvironment.
  • Developing next-generation inhibitors targeting stress-response proteins in cancer therapy.
  • Mentoring the next wave of researchers in innovative medicinal chemistry.

🌏 CONCLUSION

Dr. Shi-liang Huang embodies a blend of academic rigor, research innovation, and educational leadership. His contributions continue to shape the future of medicinal chemistry, with a legacy that inspires collaboration, discovery, and impactful solutions in cancer therapy.

📊🔬NOTABLE PUBLICATION:
  • A Novel HSF1 Activator Ameliorates Non-Alcoholic Steatohepatitis by Stimulating Mitochondrial Adaptive Oxidation
    • Authors: Rao, Y.; Li, C.; Hu, Y.-T.; Ye, J.-M.; Huang, Z.-S.
    • Journal: British Journal of Pharmacology
    • Year: 2022

 

  • Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex
    • Authors: Li, M.-L.; Yuan, J.-M.; Yuan, H.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2022

 

  • Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy
    • Authors: Pan, X.; Mao, T.-Y.; Mai, Y.-W.; Huang, Z.-S.; Huang, S.-L.
    • Journal: Molecules
    • Year: 2022

 

  • Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer
    • Authors: Jiang, X.-C.; Tu, F.-H.; Wei, L.-Y.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2022

 

  • Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer
    • Authors: Xu, Y.-H.; Hu, Y.-T.; Xu, S.-M.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2023

Ms. Xin Xin | Cancer Biomarkers | Best Researcher Award

Ms. Xin Xin | Cancer Biomarkers | Best Researcher Award

Shanghai University of Traditional Chinese Medicine | China

AUTHOR PROFILE

Scopus

📚 EARLY ACADEMIC PURSUITS

Xin Xin’s academic journey is rooted in the integration of Traditional Chinese Medicine (TCM) with Western medicine, particularly focusing on reproductive health and gynecology. He obtained a Bachelor of Science in Chinese Medicine from Shandong University of Traditional Chinese Medicine. His academic foundation continued to expand as he pursued an MD in Gynecology of Traditional Chinese Medicine, further honing his expertise in reproductive diseases. Xin is currently working towards his PhD in Clinical Chinese Medicine Integrated with Western Medicine at Shanghai University of Traditional Chinese Medicine, under the guidance of Advisor Jinfu Zhang.

💼 PROFESSIONAL ENDEAVORS

Xin Xin’s professional career is centered on bridging the gap between traditional and modern medical approaches. He is particularly involved in the clinical and mechanistic research of reproductive diseases, with a primary focus on polycystic ovary syndrome (PCOS). His work aims to enhance diagnostic methods and treatment approaches through a combined understanding of TCM and Western medicine. Xin has contributed significantly to clinical studies and investigations, with his academic path guided by prominent scholars in the field, including Dr. Fang Lian and Dr. Haicui Wu during his MD program at Shandong University.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON CANCER BIOMARKERS

Xin Xin’s research is notable for its emphasis on the pathogenesis, diagnosis, and treatment of reproductive diseases, with a particular focus on PCOS. He has undertaken several groundbreaking projects, one of which explores the expression of long non-coding RNAs (lncRNA) in follicular fluid exosomes of patients with obesity and PCOS using high-throughput sequencing technology. This research represents an effort to better understand the molecular mechanisms behind PCOS and to uncover novel biomarkers for early detection and intervention.

Another area of Xin’s research explores the role of Bone Morphogenetic Protein 6 (BMP6) in regulating Pentraxin 3 expression in human granulosa lutein cells in women with PCOS. His studies are pivotal in uncovering molecular markers and pathways that could lead to more effective therapeutic strategies.

🌟 IMPACT AND INFLUENCE

Xin Xin’s work has garnered attention within the scientific community due to his innovative approach of combining traditional Chinese medicine with Western medical techniques. His research aims to contribute to the development of a more holistic and comprehensive understanding of reproductive diseases. By investigating both the molecular and clinical aspects of PCOS, Xin is pushing boundaries in reproductive health research. His work has the potential to change how clinicians approach the treatment of polycystic ovary syndrome, a condition that affects millions of women worldwide.

📑 ACADEMIC CITES

Although his research is relatively recent, Xin Xin’s work is beginning to attract attention in the academic community. His publications on the expression of lncRNAs and BMP6 in PCOS are contributing to the growing body of knowledge on this common reproductive disorder. These publications are expected to increase in citations as they influence future studies and clinical approaches. His articles, including “Exploring lncRNA expression in follicular fluid exosomes of patients with obesity and polycystic ovary syndrome” (2024), and “Bone Morphogenetic Protein 6 Induces Downregulation of Pentraxin 3 Expression in Human Granulosa Lutein Cells in Women With Polycystic Ovary Syndrome” (2024), are already making a mark in reproductive health research.

🌱 LEGACY AND FUTURE CONTRIBUTIONS

Looking ahead, Xin Xin is poised to continue his impactful contributions to the field of reproductive medicine. With a focus on integrating TCM with Western medical practices, his future research may lead to the development of novel therapeutic modalities for PCOS and other reproductive diseases. He is likely to remain an influential figure in the field of gynecology, particularly in areas that explore the intersections between traditional and modern approaches to healthcare. His research has the potential to influence both clinical practices and medical education, paving the way for new, more integrated methods of treating complex reproductive health conditions.

In the coming years, Xin Xin’s work will likely expand into further clinical trials and studies, contributing to the refinement of treatments for women with PCOS, and potentially providing a more personalized and effective approach to reproductive medicine globally.

✨Conclusion:

Xin Xin’s academic and professional journey stands as a testament to the growing importance of integrating traditional and modern medical practices in addressing complex health conditions. His dedicated research in reproductive medicine, particularly focusing on polycystic ovary syndrome (PCOS), has already made valuable contributions to understanding its pathogenesis and improving diagnostic and therapeutic methods. By exploring innovative molecular mechanisms and combining high-throughput sequencing technology with traditional Chinese medicine, Xin is laying the groundwork for a more holistic approach to treating reproductive diseases.

📊🔬NOTABLE PUBLICATION:
  • Reproductive outcomes of dual trigger with combination GnRH agonist and hCG versus trigger with hCG alone in women undergoing IVF/ICSI cycles: a retrospective cohort study with propensity score matching
    • Authors: Dong, L., Lian, F., Wu, H., Yu, X., Xin, X.
    • Journal: BMC Pregnancy and Childbirth
    • Year: 2022

 

  • The effect of large follicle puncture and aspiration on the outcomes of IVF-ET in patients with asynchronized follicles under the long GnRH-a protocol: a retrospective cohort study
    • Authors: Wang, Y., Pang, C., Wu, H., Xin, X., Lian, F.
    • Journal: BMC Pregnancy and Childbirth
    • Year: 2023

 

  • Effect of human chorionic gonadotropin injection before frozen-thawed embryo transfer: A retrospective cohort study
    • Authors: Xin, X., Dong, L., Guan, L., Li, J., Lian, F.
    • Journal: Medicine (United States)
    • Year: 2023

 

  • Clinical Efficacy and Mechanism of Erzhi Tiangui Prescription in Treatment of Patients with Repeated Implantation Failure of Kidney Deficiency Syndrome Based on sPD-1 and Th17/Treg Cytokines
    • Authors: Wang, Y., Pang, C., Wu, H., Xin, X., Lian, F.
    • Journal: Chinese Journal of Experimental Traditional Medical Formulae
    • Year: 2023

 

  • Total knee arthroplasty in patients with Klippel Trenaunay syndrome and knee osteoarthritis: A case report and a literature review
    • Authors: Li, J., Lv, G., Han, Z., Xin, X.
    • Journal: Medicine (United States)
    • Year: 2024

Assoc Prof Dr. Elcin Aydin | Endometrium Cancer | Best Researcher Award

Assoc Prof Dr. Elcin Aydin | Endometrium Cancer | Best Researcher Award

University of Health Sciences, Izmir | Turkey

AUTHOR PROFILE

Scopus

Orcid ID

EARLY ACADEMIC PURSUITS

  • Assoc Prof Dr. Elçin Aydın’s academic journey began with a strong foundation in medical sciences. She pursued her education with a focus on radiology, demonstrating a keen interest in the diagnostic and therapeutic applications of imaging technologies. Her early academic pursuits laid the groundwork for her specialization in abdominal and genitourinary radiology.

PROFESSIONAL ENDEAVORS

  • Dr. Aydın is currently affiliated with the University of Health Sciences in Izmir, Turkey, and works at Izmir City Hospital. Her professional endeavors have been marked by a commitment to clinical excellence and academic rigor. She has been an active member of prestigious organizations such as the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), the European Congress of Radiology (ECR), and the European Society of Urogenital Radiology (ESUR).

CONTRIBUTIONS AND RESEARCH FOCUS

  • Dr. Aydın has made significant contributions to the field of radiology through her research and clinical work. She has published 14 original articles in SCI-EXP indexed journals and authored 4 case studies, highlighting her expertise in abdominal and genitourinary radiology. Her research focuses on the diagnostic accuracy and clinical applications of imaging techniques in these areas, aiming to improve patient outcomes through advanced radiological practices.

IMPACT AND INFLUENCE

  • Through her scholarly publications and clinical practice, Dr. Aydın has had a considerable impact on the field of radiology. Her work is frequently cited by peers, reflecting the influence of her research on contemporary radiological practices. Her involvement in ESGAR, ECR, and ESUR underscores her influence within the radiological community, where she contributes to the advancement of knowledge and practice standards.

ACADEMIC CITATIONS

  • Dr. Aydın’s research has garnered significant academic attention, with numerous citations in prominent radiological journals. Her studies on abdominal and genitourinary radiology are referenced by other researchers and clinicians, indicating the high regard in which her work is held. This academic recognition is a testament to the quality and relevance of her research contributions.

LEGACY AND FUTURE CONTRIBUTIONS ON ENDOMETRIUM CANCER

  • Dr. Aydın’s legacy in the field of radiology is characterized by her dedication to advancing medical imaging and improving patient care. Looking ahead, she is poised to continue her impactful research and clinical work, with a focus on innovative imaging techniques and their applications in abdominal and genitourinary radiology. Her future contributions are expected to further enhance the understanding and practice of radiology, benefiting both the medical community and patients.

OTHER IMPORTANT TOPICS

TEACHING AND MENTORSHIP

  • In addition to her research and clinical responsibilities, Dr. Aydın is deeply committed to teaching and mentoring the next generation of radiologists. Her role at the University of Health Sciences allows her to shape the education and training of medical students and residents, ensuring the continued growth and development of the field.

COLLABORATIVE PROJECTS

  • Dr. Aydın actively engages in collaborative projects with other institutions and researchers. These collaborations enable the sharing of knowledge and expertise, fostering innovation and improving radiological practices globally. Her collaborative efforts have resulted in several joint publications and research initiatives.

PROFESSIONAL DEVELOPMENT

  • Continuous professional development is a cornerstone of Dr. Aydın’s career. She regularly participates in international conferences, workshops, and training programs to stay abreast of the latest advancements in radiology. This commitment to lifelong learning ensures that she remains at the forefront of her field, providing the highest standard of care to her patients.

 

📊🔬Notable Publication:

Extrapulmonary Tuberculosis: An Old but Resurgent Problem

  • Authors: Baykan, A.H., Sayiner, H.S., Aydin, E., Inan, I., Erturk, S.M.
    Journal: Insights into Imaging
  • Year: 2022

 

Quantitative Analysis of the Olfactory System in COVID-19: An MR Imaging Study

  • Authors: Altunisik, E., Baykan, A.H., Sahin, S., Aydin, E., Erturk, S.M.
    Journal: American Journal of Neuroradiology
  • Year: 2021

 

Primary Breast Tuberculosis: Imaging Findings of a Rare Disease

  • Authors: Baykan, A.H., Sayiner, H.S., Inan, I., Aydin, E., Erturk, S.M.
    Journal: Insights into Imaging
  • Year: 2021

 

Reliability of Real-Time Sonoelastography in the Diagnosis of Supraspinatus Tendinopathy

  • Authors: Aydın, E., Söylev, G.Ö., Muratlı, S.K., Tekindal, M.A., Ağıldere, M.
    Journal: Ultrasound Quarterly
  • Year: 2021

 

Optical Coherence Tomography-Angiography Findings of Prediabetic Patients

  • Authors: Emre, S., Altin, C., Ulusoy, M.O., Aydin, E.
    Journal: Oman Journal of Ophthalmology
  • Year: 2024