Prof. Yingfen Ying | Tumors | Women Researcher Award

Prof. Yingfen Ying | Tumors | Women Researcher Award

Wenzhou Medical University | China

AUTHOR PROFILE

Scopus

PROFESSOR YINGFEN YING: A DISTINGUISHED MEDICAL PROFESSIONAL 👩‍⚕️🌍

EARLY ACADEMIC PURSUITS 🎓✨

Professor Yingfen Ying embarked on her academic journey with a strong focus on medical sciences, demonstrating an early aptitude for research and clinical excellence. Her academic foundation was fortified through rigorous education at Wenzhou Medical University, where she gained critical knowledge and skills that paved the way for her distinguished career. She further enriched her expertise as a visiting scholar at the University of British Columbia in Canada, a testament to her global academic vision.

PROFESSIONAL ENDEAVORS 💼🏥

Professor Ying has made significant strides as an Associate Chief Physician and master’s supervisor at Wenzhou Medical University. Her roles extend to various esteemed positions, including:

  • Member of the Obstetrics and Gynecology Rehabilitation Committee, Chinese Rehabilitation Medicine Association.
  • Vice Chairwoman of the Youth Committee, Reproductive Medicine Branch, Zhejiang Society of Traditional Chinese and Western Medicine.
  • Member of the Obstetrics and Gynecology Branch, Zhejiang Society of Translational Medicine.
    She is also affiliated with prominent international organizations, such as the American Society of Reproductive Medicine and the European Society of Human Reproduction and Embryology.

CONTRIBUTIONS AND RESEARCH FOCUS 🔬📚

Professor Ying’s primary research interests center on the mechanistic study of environmental endocrine disruptors and reproductive endocrine diseases. Her investigations delve into the interplay between environmental factors and hormonal imbalances, significantly advancing our understanding of infertility diseases. She has led multiple national and international research projects, including those funded by the National Natural Science Foundation of China.

IMPACT AND INFLUENCE 🌟🌏

Professor Ying’s work has had far-reaching impacts in the field of reproductive medicine. She has authored nearly 30 SCI-indexed papers, contributing valuable insights and advancements to the global medical community. Her research continues to influence clinical practices and guide innovative therapeutic approaches for infertility.

ACADEMIC CITES AND PATENT ACHIEVEMENTS 📜🔑

Professor Ying’s extensive research portfolio has garnered numerous citations in high-impact journals. Additionally, she holds a European patent, exemplifying her contributions to advancing medical technology and treatment methodologies on a global scale.

LEGACY AND FUTURE CONTRIBUTIONS 🌟🚀

As a trailblazer in reproductive medicine, Professor Yingfen Ying’s legacy is defined by her commitment to advancing medical science, mentoring future generations, and improving patient outcomes. Her ongoing projects and international collaborations promise continued breakthroughs, ensuring her work remains at the forefront of reproductive health and endocrine research.

ADDITIONAL HIGHLIGHTS 🌐📖

  • Active member of youth committees in Zhejiang’s medical and scientific communities, fostering innovation and development among emerging scholars.
  • Her dedication to integrating traditional Chinese and Western medicine highlights a holistic approach to patient care and research.
  • International affiliations reflect her commitment to global medical advancements, strengthening ties between diverse medical communities.

CONCLUSION 🌟🏆

Professor Yingfen Ying exemplifies excellence in the fields of reproductive medicine and endocrine research. Her dedication to uncovering the mechanisms of infertility diseases and environmental endocrine disruptors has advanced both science and clinical practice. Through her leadership roles, impactful publications, and international collaborations, she has established herself as a global authority and advocate for holistic and innovative approaches to healthcare.

 

📊🔬NOTABLE PUBLICATION:
  • Title: Halogen atoms determine the inhibitory potency of halogenated bisphenol A derivatives on human and rat placental 11β-hydroxysteroid dehydrogenase 2
    Authors: Shi, L., Zhang, B., Ying, Y., Ge, R.-S., Liu, Y.
    Journal: Food and Chemical Toxicology
    Year: 2023

 

  • Title: Inhibitory effects of parabens on human and rat 17β-hydroxysteroid dehydrogenase 1: Mechanisms of action and impact on hormone synthesis
    Authors: Chen, Z., Gong, C., Tang, Y., Ge, R.-S., Ying, Y.
    Journal: Toxicology
    Year: 2024

 

  • Title: Per- and polyfluoroalkyl substances inhibit human and rat 17β-hydroxysteroid dehydrogenase 1: Quantitative structure-activity relationship and molecular docking analysis
    Authors: Wen, C., Chen, H., Tang, Y., Chen, C., Chen, S.
    Journal: Ecotoxicology and Environmental Safety
    Year: 2024

 

  • Title: Leydig cell development in pubertal male rats is blocked by perfluorotetradecanoic acid through decreasing AMPK-mTOR-autophagy pathway
    Authors: Tang, Y., Shi, L., Wang, S., Ge, R.-S., Ying, Y.
    Journal: Toxicology Letters
    Year: 2023

 

  • Title: Structure-activity relationship and in silico docking analysis of dicarboximide fungicides on 17β-hydroxysteroid dehydrogenase 1 of human, rat, and pig
    Authors: Chen, H., Chen, S., Tang, Y., Ge, R.-S., Duan, P.
    Journal: Ecotoxicology and Environmental Safety
    Year: 2025

Assoc. Prof. Dr. Shi-liang Huang | Tumor | Best Researcher Award

Assoc. Prof. Dr. Shi-liang Huang | Tumor | Best Researcher Award

Sun Yat-sen University | China

AUTHOR PROFILE

Scopus

ORCID ID

🧑‍🔬 DR. SHI-LIANG HUANG

Associate Professor in Medicinal Chemistry
Sun Yat-sen University, People’s Republic of China

🎯 OBJECTIVE

Dedicated Associate Professor specializing in Medicinal Chemistry, with a passion for driving innovation in drug discovery and development, focusing on the tumor microenvironment and the heat shock response.

📘 EARLY ACADEMIC PURSUITS

Dr. Huang’s academic journey began with a solid foundation in Chemistry and Biochemistry, laying the groundwork for a distinguished career. After excelling in undergraduate studies, Dr. Huang pursued advanced degrees in Medicinal Chemistry, demonstrating exceptional aptitude for research and innovation.

Key achievements during this phase include:

  • Master’s Thesis: Groundbreaking work on natural product derivatives for therapeutic applications.
  • Doctoral Research: Advanced studies on the mechanisms of small molecules in altering biochemical pathways.

🏢 PROFESSIONAL ENDEAVORS

As an Associate Professor at Sun Yat-sen University, Dr. Huang has significantly contributed to the university’s reputation as a leading institution in medicinal research. His professional journey is marked by:

  • Leading Interdisciplinary Teams: Collaborating with experts in oncology, biochemistry, and computational modeling.
  • Research Innovation: Pioneering techniques in synthesizing inhibitors targeting heat shock proteins (HSPs) and heat shock factor 1 (HSF1).
  • Teaching Excellence: Mentoring students in natural medicinal chemistry and drug design methodologies.

🧪 CONTRIBUTIONS AND RESEARCH FOCUS

Dr. Huang’s work revolves around integrating bioorganic chemistry with tumor microenvironment studies to innovate cancer therapies. Key contributions include:

  • Medicinal Chemistry: Developing novel molecules with high specificity for cancer-related targets.
  • Natural Product Exploration: Isolating and modifying natural compounds to enhance their therapeutic potential.
  • Heat Shock Response Modulation: Designing inhibitors to disrupt HSF1 and HSP pathways, which are critical in cancer cell survival under stress.
  • Tumor Microenvironment Studies: Investigating how microenvironmental factors influence drug efficacy.

🌟 IMPACT AND INFLUENCE

Dr. Huang’s research has had a profound impact on the scientific community and beyond:

  • Published Works: Author of numerous peer-reviewed articles in high-impact journals.
  • Citations and Recognition: Garnered widespread academic citations, reflecting the influence and applicability of his research.
  • Collaboration and Leadership: Actively involved in global collaborations, enhancing the translational impact of his findings.

📊 ACADEMIC CITATIONS AND METRICS

Dr. Huang’s academic metrics underscore his scholarly contributions:

  • H-Index: Demonstrates significant citation impact in medicinal chemistry and oncology.
  • Published Articles: Over 50 research papers, including breakthroughs in bioorganic and natural medicinal chemistry.
  • Research Grants: Secured funding for multiple national and international projects.

🏆 LEGACY AND FUTURE CONTRIBUTIONS

As a visionary in drug discovery, Dr. Huang aspires to expand his research impact by:

  • Advancing precision medicine approaches tailored to the tumor microenvironment.
  • Developing next-generation inhibitors targeting stress-response proteins in cancer therapy.
  • Mentoring the next wave of researchers in innovative medicinal chemistry.

🌏 CONCLUSION

Dr. Shi-liang Huang embodies a blend of academic rigor, research innovation, and educational leadership. His contributions continue to shape the future of medicinal chemistry, with a legacy that inspires collaboration, discovery, and impactful solutions in cancer therapy.

📊🔬NOTABLE PUBLICATION:
  • A Novel HSF1 Activator Ameliorates Non-Alcoholic Steatohepatitis by Stimulating Mitochondrial Adaptive Oxidation
    • Authors: Rao, Y.; Li, C.; Hu, Y.-T.; Ye, J.-M.; Huang, Z.-S.
    • Journal: British Journal of Pharmacology
    • Year: 2022

 

  • Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex
    • Authors: Li, M.-L.; Yuan, J.-M.; Yuan, H.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2022

 

  • Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy
    • Authors: Pan, X.; Mao, T.-Y.; Mai, Y.-W.; Huang, Z.-S.; Huang, S.-L.
    • Journal: Molecules
    • Year: 2022

 

  • Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer
    • Authors: Jiang, X.-C.; Tu, F.-H.; Wei, L.-Y.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2022

 

  • Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal Cancer
    • Authors: Xu, Y.-H.; Hu, Y.-T.; Xu, S.-M.; Chen, S.-B.; Huang, Z.-S.
    • Journal: Journal of Medicinal Chemistry
    • Year: 2023