Zu-Chian Chiang | Biomedicine | Best Researcher Award

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Dr. Zu-Chian Chiang | Biomedicine | Best Researcher Award

Fujian Normal University | China

Author Profile

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🔬 Dr. Zu-Chian Chiang, Ph.D.

Postdoctoral Fellow | Biomedical Research & Targeted Cancer Therapy Specialist 🧪🧬🎯
Fujian Normal University, Biomedical Research Center of Southern China

Dr. Zu-Chian Chiang is a distinguished Postdoctoral Fellow at the Biomedical Research Center of Southern China, Fujian Normal University, Qishan Campus, in Fuzhou, China. With a strong foundation in Materials and Chemical Engineering (Ph.D., National United University, Taiwan) and Chemistry (M.S., Tunghai University, Taiwan), Dr. Chiang has dedicated his academic journey to the intersection of materials science, chemistry, and biomedical innovation.

His research interests span a broad range of cutting-edge biomedical fields, including:
🔹 Functional peptide synthesis for cancer and bone tissue applications
🔹 Development of biomicro/macro-molecular complexes for regenerative medicine
🔹 Design of Antibody Drug Conjugates (ADCs) for targeted cancer therapy
🔹 Engineering of aptamers as blockers, agonists, or antagonists in cancer treatment

💡 Dr. Chiang has also contributed to academia through teaching roles, serving as a Teaching Assistant in Organic Chemistry and Chemical Engineering Thermodynamics at National United University.

🏆 Awards & Honors

  • 2020: Science and Technology Commissioner, Quanzhou, Fujian Province

  • 2017: Chairman Award, Miaoli Southeast Rotary Club, Rotary International Taiwan

  • 2016: Biotech Elite Training Reserve Program Awardee, National Taiwan University, Ministry of Science and Technology

🌐 Professional Affiliations & Contributions

  • Peer Reviewer, International Journal of Biological Macromolecules

  • Chief Club President (CP), Miaoli Xindong Satellite Rotary Club, Rotary International District 3501

  • Committee Member, Chinese Rotary Education Foundation (West District Chapter)

  • Member, Taiwan Biochemical Society 🧬

  • Member, Chinese Chemical Society ⚗️

  • Member, Chinese Society of Cell Biology 🔬

Dr. Chiang continues to blend his expertise in chemistry and biomedical engineering to push forward translational research, particularly in the field of cancer therapeutics and regenerative biomaterials.

🛡️ Conclusion

Dr. Zu-Chian Chiang stands at the forefront of interdisciplinary biomedical research, merging materials science, chemistry, and biotechnology to pioneer novel solutions in cancer therapy and regenerative medicine. His dedication to scientific advancement, combined with his active involvement in academic, professional, and community networks, highlights his role as a passionate innovator and collaborative leader in the global biomedical field. With a strong track record and a clear vision, Dr. Chiang continues to make impactful contributions that bridge the gap between cutting-edge research and clinical application. 🌍🔬💡

📊🔬NOTABLE PUBLICATION:

1. Development of Novel CD47-Specific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer In Vitro and In Vivo

Authors: Zu-Chian Chiang*, Shan Xu, Xiangqian Zhao, Min Liu*, Jizhen Lin*, Qi Chen*
Journal: Frontiers in Oncology
Year: 2022

2. Generation and Characterization of 7DC-DM1: A Non-Cleavable CD47-Targeting Antibody–Drug Conjugate with Antitumor Effects

Authors: Zu-Chian Chiang*, Shubin Fang, Yangkun Shen, Jizhen Lin, Qi Chen
Journal: International Journal of Biological Macromolecules
Year: 2025

3. Strengthening Effect of Thalidomide Combined with Anti-PD1 Antibody on Enhancing Immunity for Lung Cancer Therapy

Authors: Qing Liu, Zu-Chian Chiang#, Xiangxian Zhao, Dong-Ya Cui, Xinxin Li, Hao Chen, Fangyu Lin, Tao Jiang, Qi Chen, Xiaoyan Lin*
Journal: Current Pharmaceutical Biotechnology
Year: 2024

4. Preparation and Characterization of Antibody–Drug Conjugates Acting on HER2-Positive Cancer Cells

Authors: Zu-Chian Chiang, Yi-Kai Chiu, Cheng-Chung Lee, Yueh-Liang Tsou, Hong-Sen Chen, Horng-Ru Hsu, Tzung-Jie Yang
Journal: PLOS ONE
Year: 2020

Dr. Wenjin Wang | Targeted Cancer Therapy | Young Scientist Award

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Dr. Wenjin Wang | Targeted Cancer Therapy | Young Scientist Award

The Chinese University of Hong Kong | China

Author Profile

Scopus

Dr. Wenjin Wang 🌟🔬

Postdoctoral Researcher | Tumor Photodynamic Therapy Expert | Biomolecular Phase Separation Investigator

Research Interests

  1. Tumor Photodynamic Therapy (PDT) 💡🎯
    • Design and synthesis of novel photosensitizers for PDT.
    • Development of tumor-targeted PDT using tumor-responsive AIE (Aggregation-Induced Emission) photosensitizers.
  2. Regulation of Biomolecular Phase Separation 🧬⚛️
    • Investigation into the phase separation behaviors of biomolecules like proteins and nucleic acids.
    • Modulation of these processes with chemical molecules to enhance understanding of intracellular organization and function.

Professional Experience

  • Postdoctoral Researcher 🏢
    The Chinese University of Hong Kong, Shenzhen (07/2022–Present)

    • Research on bioapplications of AIE materials under Prof. Ben Zhong Tang.
  • Biochemical Engineer 🧪
    Shenzhen BGI Research Institute (10/2017–09/2018)

    • Designed and optimized unnatural nucleotides for sequencing applications.
  • Laboratory Assistant 🔬
    Peking University Shenzhen Graduate School (11/2016–10/2017)

    • Focused on unnatural amino acids and asymmetric carbene O-H bond insertion catalysis by myoglobin proteins.
  • Research Associate 💊
    Tianjin Institute of Pharmaceutical Research (08/2014–11/2016)

    • Developed new hypoglycemic drugs through innovative designs and research.

Education

  • Ph.D. in Chemical Biology 🧫
    Sun Yat-Sen University (09/2018–06/2022)

    • Thesis: Antitumor mechanisms of metal complexes and their regulation on biomolecular phase separation behavior.
  • M.S. in Pharmacy 💊
    Tianjin Medical University (09/2012–06/2015)

    • Research: Development of SGLT2 inhibitors and hypoglycemic activity evaluation.
  • B.S. in Pharmacy 🏥
    Tianjin Medical University (09/2008–06/2012)

Grants and Funding 💰📚

  1. National Natural Science Foundation of China
    • Ruthenium Complexes and Lipid Phase Separation in Antitumor Research (2024–2026, RMB 300K, Principal Investigator).
  2. China Postdoctoral Science Foundation
    • GGT-Activated AIE Photosensitizers for Tumor Photodynamic Therapy (2022–2025, RMB 80K, Principal Investigator).
  3. Shenzhen Medical Research Fund
    • Manipulable Aggregation of AIE Photosensitizers for Enhanced Tumor PDT (2025–2027, RMB 800K, Principal Investigator).
  4. National Natural Science Foundation of China
    • Phase Separation Mechanism of Antitumor Phosphor Metal Complexes (2022–2025, RMB 630K, Major Participant).
  5. Yunnan Province Science and Technology Plan
    • Aggregate Induced Luminescence in Biomass Resources (2024–2026, RMB 2000K, Major Participant).

Awards and Honors 🏆✨

  • Excellent Postdoctoral Doctor (Shenzhen, 12/2023).
  • National Scholarship for Doctoral Students (12/2021).
  • “Fran” Excellent Thesis Scholarship (Second Class, Sun Yat-sen University, 11/2021).
  • Excellent Wall Poster Award (32nd Academic Annual Meeting, Chinese Chemical Society, 04/2021).

Key Contributions 📈

Dr. Wang’s groundbreaking research combines innovative photodynamic therapies and the manipulation of biomolecular phase separation, driving advancements in cancer treatment and molecular biology.

📊🔬NOTABLE PUBLICATION:
  • Title: Multi-Stimuli-Responsive and Cell Membrane Camouflaged Aggregation-Induced Emission Nanogels for Precise Chemo-photothermal Synergistic Therapy of Tumors
    • Authors: Zhang, L.; Wang, Z.; Zhang, R.; … Zhao, Z.; Tang, B.Z.
    • Journal: ACS Nano
    • Year: 2023

 

  • Title: Multi-site isomerization of synergistically regulated stimuli-responsive AIE materials toward multi-level decryption
    • Authors: Zhong, W.; Zhang, J.; Lin, Y.; … Cai, X.-M.; Tang, B.Z.
    • Journal: Chemical Science
    • Year: 2024

 

  • Title: Chromene-based BioAIEgens: ‘in-water’ synthesis, regiostructure-dependent fluorescence and ER-specific imaging
    • Authors: Cai, X.-M.; Lin, Y.; Zhang, J.; … Zhao, Z.; Tang, B.Z.
    • Journal: National Science Review
    • Year: 2023

 

  • Title: Natural Acceptor of Coumarin-Isomerized Red-Emissive BioAIEgen for Monitoring Cu²⁺ Concentration in Live Cells via FLIM
    • Authors: Cai, X.-M.; Li, S.; Wang, W.-J.; … Zhao, Z.; Tang, B.Z.
    • Journal: Advanced Science
    • Year: 2024

 

  • Title: Room Temperature Phosphorescent Nanofiber Membranes by Bio-Fermentation
    • Authors: Nie, X.; Gong, J.; Ding, Z.; … Qiu, Z.; Tang, B.Z.
    • Journal: Advanced Science
    • Year: 2024