Dr. Wenjin Wang | Targeted Cancer Therapy | Young Scientist Award

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Dr. Wenjin Wang | Targeted Cancer Therapy | Young Scientist Award

The Chinese University of Hong Kong | China

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Dr. Wenjin Wang 🌟🔬

Postdoctoral Researcher | Tumor Photodynamic Therapy Expert | Biomolecular Phase Separation Investigator

Research Interests

  1. Tumor Photodynamic Therapy (PDT) 💡🎯
    • Design and synthesis of novel photosensitizers for PDT.
    • Development of tumor-targeted PDT using tumor-responsive AIE (Aggregation-Induced Emission) photosensitizers.
  2. Regulation of Biomolecular Phase Separation 🧬⚛️
    • Investigation into the phase separation behaviors of biomolecules like proteins and nucleic acids.
    • Modulation of these processes with chemical molecules to enhance understanding of intracellular organization and function.

Professional Experience

  • Postdoctoral Researcher 🏢
    The Chinese University of Hong Kong, Shenzhen (07/2022–Present)

    • Research on bioapplications of AIE materials under Prof. Ben Zhong Tang.
  • Biochemical Engineer 🧪
    Shenzhen BGI Research Institute (10/2017–09/2018)

    • Designed and optimized unnatural nucleotides for sequencing applications.
  • Laboratory Assistant 🔬
    Peking University Shenzhen Graduate School (11/2016–10/2017)

    • Focused on unnatural amino acids and asymmetric carbene O-H bond insertion catalysis by myoglobin proteins.
  • Research Associate 💊
    Tianjin Institute of Pharmaceutical Research (08/2014–11/2016)

    • Developed new hypoglycemic drugs through innovative designs and research.

Education

  • Ph.D. in Chemical Biology 🧫
    Sun Yat-Sen University (09/2018–06/2022)

    • Thesis: Antitumor mechanisms of metal complexes and their regulation on biomolecular phase separation behavior.
  • M.S. in Pharmacy 💊
    Tianjin Medical University (09/2012–06/2015)

    • Research: Development of SGLT2 inhibitors and hypoglycemic activity evaluation.
  • B.S. in Pharmacy 🏥
    Tianjin Medical University (09/2008–06/2012)

Grants and Funding 💰📚

  1. National Natural Science Foundation of China
    • Ruthenium Complexes and Lipid Phase Separation in Antitumor Research (2024–2026, RMB 300K, Principal Investigator).
  2. China Postdoctoral Science Foundation
    • GGT-Activated AIE Photosensitizers for Tumor Photodynamic Therapy (2022–2025, RMB 80K, Principal Investigator).
  3. Shenzhen Medical Research Fund
    • Manipulable Aggregation of AIE Photosensitizers for Enhanced Tumor PDT (2025–2027, RMB 800K, Principal Investigator).
  4. National Natural Science Foundation of China
    • Phase Separation Mechanism of Antitumor Phosphor Metal Complexes (2022–2025, RMB 630K, Major Participant).
  5. Yunnan Province Science and Technology Plan
    • Aggregate Induced Luminescence in Biomass Resources (2024–2026, RMB 2000K, Major Participant).

Awards and Honors 🏆✨

  • Excellent Postdoctoral Doctor (Shenzhen, 12/2023).
  • National Scholarship for Doctoral Students (12/2021).
  • “Fran” Excellent Thesis Scholarship (Second Class, Sun Yat-sen University, 11/2021).
  • Excellent Wall Poster Award (32nd Academic Annual Meeting, Chinese Chemical Society, 04/2021).

Key Contributions 📈

Dr. Wang’s groundbreaking research combines innovative photodynamic therapies and the manipulation of biomolecular phase separation, driving advancements in cancer treatment and molecular biology.

📊🔬NOTABLE PUBLICATION:
  • Title: Multi-Stimuli-Responsive and Cell Membrane Camouflaged Aggregation-Induced Emission Nanogels for Precise Chemo-photothermal Synergistic Therapy of Tumors
    • Authors: Zhang, L.; Wang, Z.; Zhang, R.; … Zhao, Z.; Tang, B.Z.
    • Journal: ACS Nano
    • Year: 2023

 

  • Title: Multi-site isomerization of synergistically regulated stimuli-responsive AIE materials toward multi-level decryption
    • Authors: Zhong, W.; Zhang, J.; Lin, Y.; … Cai, X.-M.; Tang, B.Z.
    • Journal: Chemical Science
    • Year: 2024

 

  • Title: Chromene-based BioAIEgens: ‘in-water’ synthesis, regiostructure-dependent fluorescence and ER-specific imaging
    • Authors: Cai, X.-M.; Lin, Y.; Zhang, J.; … Zhao, Z.; Tang, B.Z.
    • Journal: National Science Review
    • Year: 2023

 

  • Title: Natural Acceptor of Coumarin-Isomerized Red-Emissive BioAIEgen for Monitoring Cu²⁺ Concentration in Live Cells via FLIM
    • Authors: Cai, X.-M.; Li, S.; Wang, W.-J.; … Zhao, Z.; Tang, B.Z.
    • Journal: Advanced Science
    • Year: 2024

 

  • Title: Room Temperature Phosphorescent Nanofiber Membranes by Bio-Fermentation
    • Authors: Nie, X.; Gong, J.; Ding, Z.; … Qiu, Z.; Tang, B.Z.
    • Journal: Advanced Science
    • Year: 2024

Prof. Elina Genina | Tumor Model | Best Researcher Award

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Prof. Elina Genina | Tumor Model | Best Researcher Award

Saratov State University | Russia

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Orcid id

Google Scholar

📚 Biography: Prof. Elina A. Genina

  • 🎓 Education:

    • Saratov State University, Saratov, Russia
      • MS in Radiophysics and Electronics, 1993
      • PhD in Biophysics, 2002
      • Dr.Sc. in Biophysics, 2017

  • 🏢 Professional Experience:

    • Full Professor, Chair of Optics and Biophotonics, Saratov State University (SSU), since 2018
    • Senior Researcher, Interdisciplinary Laboratory on Biophotonics, Tomsk State University, 2014–2018
    • Associate Professor, Chair of Optics and Biophotonics, SSU, 2003–2018
    • Assistant Professor, Chair of Optics, SSU, 2002–2003
    • Engineer, Chair of Optics, SSU, 2000–2002
    • PhD Student, Chair of Optics, SSU, 1996–2001
    • Engineer, Institute of Chemistry, SSU, 1993–1997

  • 🌟 Honors and Awards:

    • George Soros PhD student awards, 1999 and 2000
    • Post-Doctoral Fellowship Award, U.S. Civilian Research and Development Foundation for the Independent States of the Former Soviet Union (CRDF), 2003
    • Welcome Trust Award, 2005
    • Nano Research Top Papers Award, 2016

  • 📚 Teaching Experience:

    • Courses on Fundamentals of Photobiology, Photomedicine, Tissue Optics, Measurement Methods in Biology and Medicine, and more

  • 📝 Research Interests:

    • Biological and medical physics, biophotonics, biomedical optics, nanobiophotonics, OCT, optical and laser measurements, photodynamic/photothermal therapy

  • 📃 Selected Papers:

    • Published numerous papers and reviews in peer-reviewed journals such as J. Biophotonics, J. Biomedical Optics, and others

  • 🎙️ Professional Activities:

    • Member of editorial boards and reviewer for various scientific journals
    • Member of international conference committees including Saratov Fall Meeting

  • 📘 Book Editor:

    • Edited “Handbook of tissue optical clearing: new prospects in optical imaging,” CRC Press, 2022

  • 🏅 Special Issues:

    • Guest editor and contributor to special issues in journals and proceedings on biophotonics technologies

📊🔬Notable Publication:

Photothermal and photodynamic therapy of tumors with plasmonic nanoparticles: challenges and prospects

Authors: Alla B Bucharskaya, Nikolai G Khlebtsov, Boris N Khlebtsov, Galina N Maslyakova, Nikita A Navolokin, Vadim D Genin, Elina A Genina, Valery V Tuchin

Journal: Materials

Year: 2022

 

Rapid ultrasound optical clearing of human light and dark skin

  • Authors: Elina A Genina, Yury I Surkov, Isabella A Serebryakova, Alexey N Bashkatov, Valery V Tuchin, Vladimir P Zharov
  • Journal: IEEE Transactions on Medical Imaging
  • Year: 2020

 

Optical clearing of tissues: issues of antimicrobial phototherapy and drug delivery

  • Authors: Valery V Tuchin, Elina A Genina, Elena S Tuchina, Anna V Svetlakova, Yulia I Svenskaya
  • Journal: Advanced Drug Delivery Reviews
  • Year: 2021

 

Optimized skin optical clearing for optical coherence tomography monitoring of encapsulated drug delivery through the hair follicles

  • Authors: Sergey M Zaytsev, Yulia I Svenskaya, Ekaterina V Lengert, Georgy S Terentyuk, Alexey N Bashkatov, Valery V Tuchin, Elina A Genina
  • Journal: Journal of Biophotonics
  • Year: 2020

 

Glycerol effects on optical, weight and geometrical properties of skin tissue

  • Authors: Vadim D Genin, Elina A Genina, Valery V Tuchin, Alexey N Bashkatov
  • Journal: Journal of Innovative Optical Health Sciences
  • Year: 2021

Dr. Lei Xia | Theranostics | Best Researcher Award

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Dr. Lei Xia | Theranostics | Best Researcher Award

Peking University Cancer Hospital |  China

Author Profile

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Orcid Id

Dr. Xia Lei, PhD 🧬

Affiliation:
Department of Nuclear Medicine, Peking University Cancer Hospital
Physician, Associate Researcher

Contact Information:
📞 Phone: 18811177191
✉️ Email: xialei9012288@126.com

Biography:

Dr. Xia Lei, PhD, currently serves as a physician and associate researcher in the Department of Nuclear Medicine at Peking University Cancer Hospital. Dr. Lei graduated from the Medical School of Peking University in 2020. His expertise and research interests lie in the innovative field of nuclear medicine, particularly focusing on the development and clinical application of radiopharmaceutical probes for tumor targeting.

His primary research areas include:

  1. Construction of Tumor-Targeted Multimodal Imaging Molecular Probes 🩻
    • Dr. Lei is dedicated to creating advanced imaging probes that can target tumors with high precision, enhancing the accuracy of tumor detection and diagnosis.
  2. Development and Preliminary Application of Novel Integrated Diagnostic and Therapeutic Probes 🧫
    • He is pioneering the integration of diagnostic and therapeutic functions into single probes, aiming to streamline and improve the effectiveness of cancer treatment.
  3. Preparation and Clinical Translation of Tumor-Targeted Radiopharmaceutical Probes 🧪
    • Dr. Lei’s work involves preparing radiopharmaceuticals that specifically target tumors and translating these innovations from the lab to clinical settings to benefit patients.

Principal Investigator in Projects:

Dr. Lei has been the principal investigator for several prestigious projects, showcasing his leadership in research and innovation:

  1. National Natural Science Foundation of China, Young Scientists Fund (NO.82202201) 🌟
    • RMB 300,000 (January 2023 – December 2025)
  2. Young Talents Support Plan by the China Association for Science and Technology (NO. YESS20220230) 🌟
    • RMB 600,000 (January 2023 – December 2025)
  3. Beijing Natural Science Foundation, General Program (NO.7242266) 🌟
    • RMB 200,000 (January 2024 – December 2026)
  4. Peking University Cancer Hospital Science Innovation and Translation Fund 🌟
    • RMB 140,000 (January 2024 – December 2024)
  5. Medical School of Peking University, Young Scientists Innovation Fund 🌟
    • RMB 40,000
  6. Internal Fund of Peking University Cancer Hospital 🌟
    • RMB 80,000
  7. Peking University Cancer Hospital Science Innovation Nurturing Fund 🌟
    • RMB 100,000

Dr. Lei’s contributions to the field of nuclear medicine are instrumental in advancing the understanding and treatment of cancer, reflecting his commitment to medical innovation and patient care.

 

📊🔬Notable Publication: