Dr.Doria Filipponi is a research scientist who received her master degree in molecular biology from Bologna University in Italy. Subsequently she completed a PhD program in stem cells biology from Roma University. Later, she moved to the Institute of Molecular and Cell Biology (Singapore) to carry out her postdoc in the laboratory of Dmitry Bulavin. During this period, Doria Filipponi made an important discovery connecting DNA-damage signaling, heterochromatin regulation and a mutation-prone environment that may enhance heterogeneity and ultimately contribute to tumor evolution. After moving to the institute for Research in Cancer and Aging in France, Doria Filipponi continued interrogating the role of DNA damage signaling in cancer. Through detailed analysis of multiple novel mouse models, Doria Filipponi uncovered an unexpected role of DNA damage-induced signaling in cancer cell reprogramming as an alternative to Cancer Stem Cell model of tumor relapse. More recently, Doria Filipponi moved to Centre Scientifique de Monaco to understand the mechanisms of stem cell plasticity in brain cancers.
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