Prof. Paolo De Simone - Oncology Therapy - Most Liked Article Award

UNIVERSITY OF PISA - Italy

Author Profile

EARLY ACADEMIC PURSUITS

Paolo De Simone graduated summa cum laude in Medicine and Surgery from the University of Rome La Sapienza. His thesis was titled "Laparoscopic cholecystectomy in the treatment of gallstone lithiasis: prospective analysis of the results of our experience" under the supervision of Prof. Raffaello Cortesini.He earned his Specialist Diploma in General Surgery summa cum laude from the University of Rome “La Sapienza”. His thesis focused on "The role of laparoscopic surgery in the treatment of benign and malignant gastric pathologies" under the guidance of Prof. Raffaello Cortesini.Paolo De Simone achieved his PhD summa cum laude in Surgical Pathophysiology.

PROFESSIONAL ENDEAVORS

Registered in the Order of Doctors-Surgeons and Dentists of the Province of Rome with registration number 46702. He also qualified to practice the medical-surgical profession at the University of Rome “La Sapienza”. He served as a Foreign Resident-Assistant at the General Surgery Service of CHU André Vésale, Université Libre de Bruxelles, Montigny-Le-Tilleul, Belgium, and at the Thoracic and Vascular Surgery Service of the Hospital Avicenne, Bobigny, France. Paolo De Simone held several medical director positions:General Surgery Unit, Civil Hospital of Vittorio Veneto (TV),Organ Transplant Unit, San Salvatore Civil Hospital, L'Aquila,Service de Chirurgie Digestive, Hopital Erasme, Université Libre de Bruxelles, Brussels,University Liver Transplantology Unit, Pisa University Hospital.Currently, he is an Associate Professor of Surgery at the University of Pisa. He was elected Director of the School of Specialization in Surgery of the Digestive System and serves as Director of the Liver Surgery and Liver Transplant Unit, AOUP.

CONTRIBUTIONS AND RESEARCH FOCUS ON ONCOLOGY THERAPY

Appointed as the Coordinator of the regional liver transplant program by DGRT of 17 December 2018, n. 1450. He also managed clinical, scientific, and educational coordination of terminal liver failure and liver transplantation (DG AOUP Resolution 852 of 09/20/2023).His research has covered areas like laparoscopic cholecystectomy, treatment of benign and malignant gastric pathologies, and liver transplantology.

IMPACT AND INFLUENCE

As Coordinator of the Liver Transplant Program of the Tuscany Region, he has significantly contributed to the advancement of liver transplantation in the region.

LEGACY AND FUTURE CONTRIBUTIONS

Paolo De Simone's legacy lies in his extensive contributions to the fields of general surgery, liver surgery, and liver transplantology. His future contributions are anticipated in enhancing liver transplant programs, furthering research in surgical pathophysiology, and mentoring the next generation of surgeons through his academic roles.

NOTABLE PUBLICATIONS

Everolimus Mitigates the Risk of Hepatocellular Carcinoma Recurrence after Liver Transplantation.

First-in-human liver transplantation from a centenarian deceased donor after brain death.

Aging with a Liver Graft: Analysis of Very Long-Term Survivors after Liver Transplantation.

An Unexpected Case of Opisthorchis felineus Infection Revealed during Liver Transplantation.

An overview of the efficacy and safety of everolimus in adult solid organ transplant recipients.

Cancer Care and management

Introduction: Cancer care and management encompass a comprehensive approach to understanding, diagnosing, treating, and supporting individuals affected by cancer. With advancements in medical science and technology, the field has evolved to provide more personalized and effective care for cancer patients.

Subtopics in Cancer Care and Management:

Early Detection and Screening: Early diagnosis is crucial for successful cancer treatment. This subtopic explores various screening methods, including mammography, colonoscopy, and genetic testing, to detect cancer at its earliest stages.

Treatment Modalities: Cancer treatment options have expanded beyond surgery, chemotherapy, and radiation therapy. Subtopics here may include immunotherapy, targeted therapy, and precision medicine approaches tailored to individual patient profiles.

Palliative Care and Symptom Management: This subtopic focuses on improving the quality of life for cancer patients through pain management, emotional support, and symptom relief, especially for those in advanced stages of the disease.

Cancer Survivorship: After completing cancer treatment, patients often face ongoing challenges related to physical and emotional well-being. Subtopics here address survivorship care plans, rehabilitation, and psychosocial support.

Nutrition and Lifestyle: Nutrition plays a crucial role in cancer prevention and management. Topics may include dietary guidelines, exercise, and lifestyle modifications for cancer patients.

Psychosocial Support: Cancer care extends beyond the physical aspect, and emotional well-being is equally important. Subtopics include counseling, support groups, and addressing the psychological impact of cancer.

Cancer Genetics and Risk Assessment: Understanding the genetic factors contributing to cancer risk and hereditary forms of cancer is vital. Topics may include genetic counseling and testing for high-risk individuals.

Patient-Centered Care: The importance of tailoring cancer care to individual patient needs is growing. This subtopic explores patient-centered approaches, shared decision-making, and patient empowerment in the treatment process.

Global Perspectives on Cancer Care: Different regions and countries face unique challenges in cancer care. This subtopic examines disparities in cancer care access, international collaborations, and global efforts to combat cancer.

These subtopics collectively contribute to a holistic approach to cancer care and management, ensuring that patients receive the best possible care throughout their cancer journey.