Introduction: Cancer metastasis is a formidable and complex process wherein cancer cells break away from their primary site, travel through the body, and establish secondary tumors at distant locations. Understanding the mechanisms and factors governing this deadly journey is essential for devising effective strategies to prevent, detect, and treat metastatic cancer.

Subtopics in Cancer Metastasis:

The Metastatic Cascade : Explore the intricate steps of the metastatic cascade, from cancer cell detachment, invasion, and intravasation into blood or lymphatic vessels to extravasation and colonization at distant sites.

Tumor Microenvironment and Metastasis : Investigate how the tumor microenvironment influences metastasis, including interactions between cancer cells and stromal cells, extracellular matrix components, and immune responses.

Metastasis-Specific Biomarkers : Examine the search for specific biomarkers and genetic signatures associated with metastatic potential, aiding in the early detection and monitoring of metastatic disease.

Targeting Metastatic Pathways : Discover novel therapeutic approaches targeting the molecular pathways and cellular mechanisms involved in metastasis, aiming to inhibit its progression and improve patient outcomes.

Metastasis Prevention and Intervention : Explore strategies to prevent metastasis or intervene at various stages of the metastatic process, including the development of anti-metastatic drugs and lifestyle modifications.