Prof. Ming-Yow Hung | Cardio-Oncology | Best Researcher Award

Taipei Medical University | Taiwan

Author Profile

Scopus

ORCID ID

Biography: Prof. Ming-Yow Hung, MD, PhD 🌟💖🩺

Name: Prof. Ming-Yow Hung
Citizenship: Taiwanese

🎓 Education:

Medical Degree: School of Medicine, College of Medicine, Chang Gung University (1989–1995).
PhD: Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine (2007–2017).

🎖 Military Service:

Lieutenant General Physician, Navy, Taiwan, Republic of China (1996–1998).

💼 Professional Roles:

Attending Cardiologist: Division of Cardiology, Shuang Ho Hospital, Taipei Medical University (2008–present).
Professor of Medicine: Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University (since 2022).

🏅 Board Certifications:

Internal Medicine (2001).
Adult Cardiology (2004).

🔬 Research Interests:

Interventional Cardiology
Echocardiography
Basic Cardiovascular Science

📜 Editorial Contributions:

Editorial Board Member:
- Enliven: Clinical Cardiology and Research (2015–present).
- Journal of Epidemiological Research (2015–present).
- SM Vascular Medicine (2015–present).
Guest Editor:
- Journal of Interventional Cardiology (2019–2020).
- Oxidative Medicine and Cellular Longevity (2023).
- Frontiers in Cardiovascular Medicine (2023).
- Life (2023).

🎯 Research Projects:

Investigating macrophage polarization in coronary artery spasm using CRISPR core facilities (2020–2021).
Mechanisms of Garcinol as α-7nAChRs Inhibitor in cardiac damage (2021–2022).
LPCAT4/GDE7 axis as therapeutic targets in coronary artery spasm (2022–2023).
SCAP/SREBPs signaling in lipoprotein(a)-induced macrophage polarization (2023–2026).

🌟 Professional Affiliations:

Fellow, American Heart Association (2013–present).
Fellow, American College of Cardiology (2014–present).
Member of multiple Taiwanese and international cardiology societies.

🏆 Honors and Awards:

Clinical Medicine Research Award, Taipei Medical University (2014, 2015).
Recognition for outstanding contributions to cardiovascular research and patient care.

Prof. Hung is renowned for his dedication to advancing cardiovascular science, particularly in coronary artery spasm and interventional cardiology. 🌍❤️

🔗 CONCLUSION

Prof. Ming-Yow Hung is a distinguished cardiologist and academic leader, whose expertise in interventional cardiology, echocardiography, and cardiovascular science has earned him national and international recognition. As a Full Professor at Taipei Medical University and a Fellow of esteemed cardiology organizations, he has made significant contributions to both clinical practice and research.

📊🔬NOTABLE PUBLICATION:

Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α 7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm
- Authors: Lin, Y.-K.; Yeh, C.-T.; Kuo, K.-T.; Hu, P.; Hung, M.-Y.
- Journal: Oxidative Medicine and Cellular Longevity
- Year: 2022

The Involvement of CXC Motif Chemokine Ligand 10 (CXCL10) and Its Related Chemokines in the Pathogenesis of Coronary Artery Disease and in the COVID-19 Vaccination: A Narrative Review
- Authors: Karimabad, M.N.; Kounis, N.G.; Hassanshahi, G.; Hung, M.-Y.; Nadimi, A.E.
- Journal: Vaccines
- Year: 2021

The Effect of Long COVID-19 Infection and Vaccination on Male Fertility: A Narrative Review
- Authors: Pourmasumi, S.; Nazari, A.; Ahmadi, Z.; Altay, S.; Kounis, N.G.
- Journal: Vaccines
- Year: 2022

“When,” “Where,” and “How” of SARS-CoV-2 Infection Affects the Human Cardiovascular System: A Narrative Review
- Authors: Kounis, N.G.; Gogos, C.; de Gregorio, C.; Velissaris, D.; Koniar, I.
- Journal: Balkan Medical Journal
- Year: 2024

Coronary Artery Spasm-Related Heart Failure Syndrome: Literature Review
- Authors: Hung, M.-J.; Yeh, C.-T.; Kounis, N.G.; Hu, P.; Hung, M.-Y.
- Journal: International Journal of Molecular Sciences
- Year: 2023

🎓 Academic and Professional Background:

Professor Yinyuan Ding obtained a Ph.D. from Peking University in 2011 and pursued postdoctoral training at UT Southwestern Medical Center, where he was later promoted to Assistant Professor in 2018. In 2019, he returned to China and joined Chongqing Medical University as a professor. His research explores tumorigenesis and glucolipid metabolic disorders, focusing on the LRP1 receptor’s role in liver and vascular signaling, with implications for novel treatments for Hepatocellular Carcinoma (HCC) and Metabolic Associated Steatohepatitis-Liver Disease (MASLD).

🔬 Research and Innovations:

Principal Investigator
2023-2026: “The role of LRP1 in hepatic glucose metabolism and HCC progression” (National Natural Science Foundation of China)
2021: “The role of Asprosin in hepatocellular carcinoma” (Chongqing Municipal Human Resources Bureau)

Participant
2015-2020: “VLDL and ApoE receptors metabolism” (NIH-NHLBI)
2011-2015: “Cell signaling and cholesterol-lipoprotein receptors” (NIH)

📝 Contributions:

Professor Ding’s groundbreaking research on LRP1 has revealed its multifaceted roles in regulating cholesterol and glucose metabolism. His work identified a critical mechanism by which LRP1 affects hepatic insulin resistance, dyslipidemia, and HCC progression. This novel insight into LRP1’s function opens pathways for innovative therapeutic strategies for cancer and metabolic disorders.

✨Conclusion:

In summary, Professor Yinyuan Ding is a distinguished expert in oncology and hepatology, with a strong focus on the molecular mechanisms of tumorigenesis and lipid metabolism disorders. His innovative research on LRP1 has led to significant breakthroughs in understanding liver disease and cancer progression, paving the way for novel therapeutic strategies. With a wealth of experience from top institutions and numerous prestigious publications and patents, Professor Ding continues to make impactful contributions to the field of cancer research, driving advancements in both basic science and clinical applications. 🌟

📊🔬NOTABLE PUBLICATION:

1. LRP1 facilitates hepatic glycogenesis by improving the insulin signaling pathway in HFD-fed mice

Authors: Guo, X., Pu, J., Tang, Z., Liu, T., Ding, Y.

Journal: Animal Models and Experimental Medicine

Year: 2024

2. Erratum: Correction: LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis

Authors: Xian, X., Ding, Y., Dieckmann, M., Tsai, S., Herz, J.

Journal: eLife

Year: 2017 (Erratum published in 2024)

3. Loss of LRP1 Promotes Hepatocellular Carcinoma Progression via UFL1-Mediated Activation of NF-κB Signaling

Authors: Guo, X., Yang, F., Liu, T., Herz, J., Ding, Y.

Journal: Advanced Science

Year: 2024