yuchang li | Chinese Medicine | Best Researcher Award

Mr. yuchang li | Chinese Medicine | Best Researcher Award

Shanxi University of Chinese Medicine | China

AUTHOR PROFILE

ORCID ID

🎓 EARLY ACADEMIC PURSUITS

Yu-chang Li is currently a student at Shanxi University of Chinese Medicine, enrolled in the Third Clinical College of Clinical Medicine, specializing in Traditional Chinese and Western Medicine. From an early stage in his academic journey, he has demonstrated a strong passion for integrating traditional Chinese medicine (TCM) with modern medical approaches. His commitment to research and academic excellence has been recognized through numerous awards and publications.

🏆 PROFESSIONAL ENDEAVORS

Yu-chang Li has made significant contributions to medical research, particularly in the field of oncology alternative medicine. His work bridges the gap between traditional Chinese medicine and Western medical practices, exploring innovative therapeutic approaches to combat life-threatening diseases.

His achievements include:
Winner of multiple prestigious awards, including:

  • National Silver Award at the 10th National College Students Basic Medical Innovation Research and Experimental Design Forum
  • Provincial Silver Award
  • Provincial Bronze Award

Published two SCI-indexed research papers, demonstrating expertise in oncology and alternative medicine.

🔬 CONTRIBUTIONS AND RESEARCH FOCUS ON CHINESE MEDICINE

Yu-chang Li’s research is centered on the role of Chinese herbal medicine in oncology, with a particular focus on the immunomodulatory effects of Astragalus membranaceus (Huangqi) and other herbal formulations.

🔹 Astragalus Injection and Osteosarcoma
One of his landmark studies, Astragalus Injection Inhibits the Growth of Osteosarcoma by Activating Cytotoxic T Lymphocyte and Targeting CTSL, investigates the use of Huangqi Injection (HQI) in treating osteosarcoma. His research highlights the immunomodulatory potential of HQI, demonstrating that its active component, Cycloastragenol (CG), enhances immune response and targets CTSL, leading to tumor suppression.

🔹 Shenqi Granules and Cerebral Ischemia-Reperfusion Injury
In another study, Shenqi Granules Enhance Recovery from Cerebral Ischemia-Reperfusion Injury by Modulating Tryptophan and Tyrosine Metabolism and Activating NFE2L2/NRF2, he explores the neuroprotective effects of Shenqi granules. His findings contribute to stroke rehabilitation research, emphasizing the potential of herbal formulations in neurological recovery.

His research provides scientific validation for traditional Chinese medicine (TCM) therapies, paving the way for their integration into modern medical treatments.

🌍 IMPACT AND INFLUENCE

Yu-chang Li’s research has had a profound impact on both oncology and alternative medicine by:
📌 Advancing integrative medicine through scientific validation of herbal treatments.
📌 Contributing to cancer immunotherapy using TCM-based approaches.
📌 Providing new perspectives on the treatment of osteosarcoma and stroke recovery.
📌 Inspiring future researchers to explore synergistic applications of Chinese and Western medicine.

📖 ACADEMIC CITATIONS AND RECOGNITION

As a young scholar, Yu-chang Li’s publications have gained recognition in the scientific community, contributing valuable insights to the fields of Chinese medicine and oncology. His work is frequently cited by researchers investigating herbal immunotherapy, oncology treatments, and neuroprotection strategies.

🔮 LEGACY AND FUTURE CONTRIBUTIONS

Yu-chang Li is poised to become a leading figure in integrative medicine, focusing on oncology and alternative therapies. His future contributions may include:
✨ Developing new herbal formulations for cancer treatment.
✨ Conducting clinical trials to further validate TCM therapies.
✨ Bridging the gap between traditional and modern medicine.
✨ Expanding the global acceptance of TCM in cancer care.

His research and innovations will undoubtedly shape the future of medicine, providing safe, effective, and scientifically backed treatments that integrate the wisdom of traditional Chinese medicine with modern scientific advancements.

🌍CONCLUSION 

Yu-chang Li is a rising scholar in integrative medicine, dedicated to advancing the scientific understanding of Traditional Chinese Medicine (TCM) and its applications in oncology and neurological disorders. His research on Astragalus Injection in osteosarcoma and Shenqi granules in stroke recovery showcases the therapeutic potential of herbal medicine, reinforcing the importance of evidence-based alternative treatments.

 

📊🔬NOTABLE PUBLICATION:
  • Title: Shenqi granules enhance recovery from cerebral ischemia-reperfusion injury by modulating tryptophan and tyrosine metabolism and activating NFE2L2/NRF2.
    Authors: Liu HX, Yang MK, Li YC, Liu CX, Li GP, Meng XL, Pei K, Wen SY
    Journal: International Journal of Phytotherapy and Phytopharmacology
    Year: 2025

 

  • Title: Astragalus injection inhibits the growth of osteosarcoma by activating cytotoxic T lymphocyte and targeting CTSL.
    Authors: Liu HX, Li YC, Su RB, Liu CX, Wen SY.
    Journal: Journal of Ethnopharmacology
    Year: 2025

Prof. Linghua Li | Cancer Science | Best Researcher Award

Prof. Linghua Li | Cancer Science | Best Researcher Award

Guangzhou Eighth People’s Hospital | China

Author Profile

ORCID ID

🌟Linghua Li, Ph.D., M.S., B.S. 🌍

Head Director, Infectious Disease Center
Guangzhou Eighth People’s Hospital, Guangzhou Medical University

👩‍⚕️Biography

Dr. Linghua Li is a distinguished physician and researcher specializing in HIV/AIDS, infectious diseases, and oncology. With over 25 years of clinical experience, she has made significant contributions to understanding and managing infectious diseases, particularly fungal infections and HIV-related complications.

Dr. Li began her academic journey at the Medical School of Peking University, earning a B.S. in Clinical Medicine in 1997. She then pursued advanced studies at Sun Yat-sen University, completing an M.S. in Internal Medicine in 2008 and a Ph.D. in Infectious Diseases in 2011. She further enriched her expertise through visiting scholar positions at UNC-Chapel Hill (2012) and Duke University (2014), focusing on infectious diseases.

As the Head Director of the Infectious Disease Center at Guangzhou Eighth People’s Hospital, Dr. Li oversees clinical trials, patient care, and research initiatives for people living with HIV and at-risk populations. She has been principal investigator (PI) or co-investigator (Co-I) on more than 20 domestic and international research programs. Notable projects include:

  • National Natural Science Foundation of China (Grant No. 81301480): Investigating the mechanism and function of Phospholipase B in the growth and pathogenicity of P. marneffei.
  • Guangdong Natural Science Foundation (Grant No. 10151006002000000): Exploring the role of Phospholipase B in P. marneffei invasion of macrophages in AIDS patients.
  • NIH Fogarty Program: Examining host factors in severe opportunistic complications of AIDS, with a focus on developing targeted prophylactic strategies.

In recent years, Dr. Li has been a Co-PI on groundbreaking HIV PrEP Phase IV clinical trials in Guangzhou, including:

  • ChiCTR2100048981 and NCT04754139: These studies focus on scaling PrEP access for key populations in China. The trial successfully enrolled 1,007 participants by 2023, with 950 already on PrEP, marking it as the largest trial of its kind in China.

Dr. Li’s work emphasizes translational medicine, data-driven public health strategies, and the implementation of novel interventions like PrEP to curb HIV transmission. Her expertise in site coordination, implementation, data collection, and analysis has been pivotal to these efforts.

🧬Key Areas of Expertise

🔬 HIV Prevention and Treatment
🌿 Opportunistic Infections
📊 Clinical Trials and Data Analysis
🧑‍⚕️ Internal and Infectious Diseases

📚Academic Background

  • B.S., Clinical Medicine, Medical School of Peking University (1997)
  • M.S., Internal Medicine, Sun Yat-sen University (2008)
  • Ph.D., Infectious Diseases, Sun Yat-sen University (2011)
  • Visiting Scholar, UNC-Chapel Hill (2012)
  • Visiting Scholar, Duke University (2014)

🔬Research Impact

🌟 Over 20 funded research projects
📄 Numerous publications in infectious disease and public health journals
📚 Active contributor to advancing HIV prevention strategies in China

Dr. Linghua Li remains a leader in the fight against infectious diseases, with a career dedicated to improving global health outcomes. 🌏✨

✨ Conclusion

Dr. Linghua Li’s career exemplifies dedication to advancing the prevention, treatment, and understanding of infectious diseases, particularly HIV/AIDS and associated complications. Through her leadership, innovative research, and clinical expertise, she has significantly impacted global health, especially in developing effective interventions like PrEP for key populations in China. Her contributions to translational medicine and public health continue to pave the way for breakthroughs in managing infectious diseases and improving the lives of those affected worldwide. 🌟🌍

📊🔬NOTABLE PUBLICATION:
  • Utilizing Protein–Peptide Hybrid Microarray for Time-Resolved Diagnosis and Prognosis of COVID-19
    • Authors: Peiyan Zheng, Baolin Liao, Jiao Yang, Hu Cheng, Zhangkai Cheng, Huimin Huang, Wenting Luo, Yiyue Sun, Qiang Zhu, Yi Deng, et al.
    • Journal: Microorganisms
    • Year: 2023

Personalized Cancer Treatment

Introduction: Personalized cancer treatment represents a paradigm shift in oncology, moving away from one-size-fits-all approaches and towards tailoring treatments based on an individual’s unique genetic, molecular, and clinical characteristics. This approach holds the promise of maximizing treatment efficacy while minimizing side effects, offering new hope for cancer patients.

Subtopics in Personalized Cancer Treatment:

Genomic Profiling: Genomic analysis of a patient’s tumor can identify specific genetic mutations and alterations that drive cancer growth. Targeted therapies are then designed to attack these specific molecular vulnerabilities, leading to more effective treatment.

Immunotherapy and Immune Profiling: Personalized cancer treatment extends to immunotherapy, where the patient’s immune system is harnessed to fight cancer. Immune profiling helps identify immune checkpoints and tumor-specific antigens, aiding in the selection of suitable immunotherapies.

Biomarker-Based Therapy: Biomarkers such as hormone receptors, HER2 status, and PD-L1 expression guide treatment decisions in breast, lung, and other cancers. Personalization ensures that patients receive therapies tailored to their tumor’s unique characteristics.

Treatment Resistance Mitigation: Personalized approaches are essential in combating treatment resistance. Continuous monitoring and adaptation of treatment regimens based on evolving tumor profiles can help overcome resistance and extend the duration of response.

Clinical Trial Matching: Personalized treatment extends to the realm of clinical trials, where patients are matched with experimental therapies that align with their tumor’s genetic makeup. This accelerates drug development and provides patients with access to cutting-edge treatments.

These subtopics highlight the transformative potential of personalized cancer treatment, emphasizing its role in optimizing patient outcomes, minimizing adverse effects, and advancing the field of oncology towards precision medicine.