Mrs. Jelena Kovacic | New Drug Development | Best Researcher Award

Faculty of Pharmacy and Biochemistry University of Zagreb | Croatia

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🎓EARLY ACADEMIC PURSUITS

Jelena Kovačić embarked on her academic journey with a Master of Science in Applied Chemistry from the Faculty of Chemical Engineering and Technology in Zagreb, completed in 2021. Her master’s thesis focused on the monitoring of degradation of selected active substances, laying a solid foundation for her research career.

🔬PROFESSIONAL ENDEAVORS

Jelena is currently a Ph.D. researcher at the Faculty of Pharmacy and Biochemistry, University of Zagreb. Her work primarily involves developing advanced analytical methods for drugs and biologically active substances, specifically targeting treatments for inflammatory bowel disease. Her role also includes involvement in stability-indicative methods, compatibility studies, and therapeutic drug monitoring.

🧪CONTRIBUTIONS AND RESEARCH FOCUS ON NEW DRUG DEVELOPMENT

Jelena’s research contributions are centered around preformulation studies, including forced degradation studies and compatibility assessments. She is also engaged in bioanalytical research, focusing on therapeutic drug monitoring and microextraction techniques. Her work involves advanced analytical techniques such as liquid chromatography (LC), mass spectrometry (MS), and chemometrics.

🌟IMPACT AND INFLUENCE

Through her active participation in international symposia and congresses, Jelena has contributed to the broader scientific community’s understanding of analytical methods and bioanalytical techniques. Her research aims to enhance the efficacy and safety of drug treatments, particularly in the context of inflammatory bowel diseases.

📚ACADEMIC CITATIONS

Jelena has established a growing presence in the academic community with her research contributions and presentations at various international platforms. Her work is expected to garner more citations as she progresses in her doctoral studies and publishes her findings.

🔮LEGACY AND FUTURE CONTRIBUTIONS

Jelena Kovačić’s future contributions are anticipated to make a significant impact on the field of pharmaceutical sciences. With her expertise in developing advanced analytical methods and her dedication to research in drug treatments, she is poised to advance the understanding and application of these methods in clinical settings, thereby shaping future research and development in the field.

🎯Conclusion

Jelena Kovačić is an emerging researcher with a strong foundation in applied chemistry and a promising trajectory in pharmaceutical sciences. Her academic pursuits and professional experiences reflect a deep commitment to advancing analytical methods and bioanalytical techniques, particularly in the treatment of inflammatory bowel disease. Through her work, she contributes valuable insights into drug development and stability, enhancing the field’s overall knowledge and application. Her active participation in international forums and her ongoing research efforts position her as a future leader in pharmaceutical research, with the potential to significantly influence drug treatment methodologies and improve patient outcomes. As she continues to develop her expertise, Jelena is set to leave a lasting impact on the scientific community

📊🔬NOTABLE PUBLICATION:

Polyphenol content and antioxidant activity of phytoestrogen containing food and dietary supplements: DPPH free radical scavenging activity by HPLC
- Authors: Klarić, D.A., Mornar, A., Kovačić, J., Brletić, I., Klarić, I.
- Journal: Acta Pharmaceutica
- Year: 2022

Accessing Lipophilicity and Biomimetic Chromatography Profile of Biologically Active Ingredients of Botanicals Used in the Treatment of Inflammatory Bowel Disease
- Authors: Jeličić, M.-L., Amidžić Klarić, D., Kovačić, J., Verbanac, D., Mornar, A.
- Journal: Pharmaceuticals
- Year: 2022

Green Solid-Phase (Micro)Extraction of Andrographolides from Human Plasma Samples Followed by UHPLC-DAD-QqQ-MS/MS Analysis
- Authors: Kovačić, J., Jeličić, M.-L., Amidžić Klarić, D., Mornar, A.
- Journal: Separations
- Year: 2023

Antioxidant Activity of Pharmaceuticals: Predictive QSAR Modeling for Potential Therapeutic Strategy
- Authors: Jeličić, M.-L., Kovačić, J., Cvetnić, M., Mornar, A., Klarić, D.A.
- Journal: Pharmaceuticals
- Year: 2022

Size exclusion chromatography as green support for forced degradation study of adalimumab
- Authors: Kovačić, J., Klarić, D.A., Turk, N., Mornar, A.
- Journal: Acta Pharmaceutica
- Year: 2023

Early Academic Pursuits

Lubna H. Tahtamouni began her academic journey at the University of Jordan, where she earned a B.Sc. in Biology in June 1997 and an M.Sc. in Biology in April 2000. Her Master's thesis, titled “The Etiological Factors Among 702 Infertile Jordanian Couples,” was supervised by Hameed Al-Hajj, Ph.D. She further pursued a Ph.D. in Developmental Biology at Colorado State University, completing her thesis on “The Role of mDia1 During the Initiation of Polarization and Migration of Chick Embryo Cardiac Fibroblasts” under the guidance of James R. Bamburg, Ph.D.

Professional Endeavors

Dr. Tahtamouni has held numerous academic and administrative positions. She has been a Professor in the Department of Biology and Biotechnology at The Hashemite University in Zarqa, Jordan, since February 2020. Previously, she served as an Associate Professor and Assistant Professor in the same department. Her administrative roles include Chair of the Department of Biology and Biotechnology and Managing the Office of Externally Funded Projects at The Hashemite University. At Colorado State University, she has been an Affiliate Faculty in the Department of Biochemistry and Molecular Biology since August 2023 and served as a Senior Research Scholar and Co-director of the Molecular Biology and Biochemistry REU program.

Contributions and Research Focus on Cancer Cell Biology

Dr. Tahtamouni’s research primarily focuses on understanding the cellular alterations leading to cancer, with specific projects on cell migration, adhesion, metastasis, mitochondrial function, apoptosis, cytoskeleton-related proteins, and cell cycle and anti-tumor drug screening. Additionally, she investigates the role of actin dynamics, mediated by the protein cofilin, in neurodegenerative diseases using induced pluripotent stem cells to model these processes.

Impact and Influence

Dr. Tahtamouni’s contributions to science have been recognized with numerous awards and honors. She was named one of the World's 100 Most Inspirational and Influential Women by the BBC in 2016 and received the Women in Science Hall of Fame award from the US Embassy in Amman, Jordan, in 2015. Her work has earned her fellowships and scholarships from prestigious institutions such as the National Institutes of Health (NIH), the U.S. National Academy of Sciences, and the L'OREAL-UNESCO for Women in Science program.

Academic Cites

Throughout her career, Dr. Tahtamouni has been involved in significant academic publishing and editorial roles. She served as Lead Guest Editor for a special issue on “Molecular Regulation of Cancer Cell Migration, Invasion and Metastasis” in Analytical Cellular Pathology and as an Assistant Editor for the Jordan Journal of Biological Sciences.

Legacy and Future Contributions

Dr. Tahtamouni’s legacy is marked by her dedication to advancing the understanding of cancer and neurodegenerative diseases. Her collaborative efforts span basic, translational, and clinical sciences, significantly impacting these fields. Looking forward, her continued research and mentorship are expected to contribute further to scientific advancements and the development of effective therapeutic strategies.

Teaching and Supervision

Dr. Tahtamouni has extensive teaching experience across various biology and biotechnology courses at The Hashemite University and Colorado State University. She has also supervised numerous training courses, particularly in assisted reproductive techniques and cytogenetics, contributing to the education and professional development of many students and researchers.