Prof. Sobhi Gomha | Chemotherapy | Best Researcher Award

Prof. Sobhi Gomha | Chemotherapy | Best Researcher Award

Islamic University of Madinah | Saudi Arabia

Author Profile

Scopus

Google Scholar

Orcid id

Personal Data:

  • Name: Sobhi Mohamed Gomha
  • Date of Birth: 1972
  • Place of Birth: Fayoum, Egypt
  • Nationality: Egyptian
  • Gender and Marital Status: Male, Married
  • Occupation: Professor of Organic Chemistry
  • Institutions:
    • Faculty of Science, Cairo University, Giza, Egypt.
    • Faculty of Science, Islamic University of Madinah, Madinah, Saudi Arabia.
  • Addresses:
    • Permanent: Faculty of Science, Cairo University, Giza 12613, Egypt; Chemistry Department
    • Resident: Faculty of Science, Islamic University of Madinah, Madinah 42351, Saudi Arabia.
  • Contact:

Certificates and Qualifications:

  • B.Sc. (Chemistry): 1995, Cairo University – Faculty of Science.
  • Pre-master courses: 1996-1997
  • M.Sc. (Organic Chemistry): 2002, Cairo University – Faculty of Science.
  • Ph.D. (Organic Chemistry): 2006, Cairo University – Faculty of Science.
  • Associate Professor: January 2012, Cairo University – Faculty of Science.
  • Full Professor: January 2017, Cairo University – Faculty of Science.

Research Interests:

  • Green Synthesis: Focus on the green synthesis of novel heterocyclic compounds using eco-friendly technologies like Microwave Irradiation, Ultrasonic radiation, Grinding, and Ionic Liquids.
  • Applications: Biological and industrial applications with an emphasis on reducing hazardous substances and energy usage.

Online Profiles:

Publications and Metrics:

  • Total Publications: 270 (257 published papers: 240 research papers, 17 review articles) + 13 books.
  • Citations:
    • Google Scholar: 6730
    • Scopus: 5600
    • Web of Science: 6280
    • ResearchGate: 6050
  • Highly Cited Papers:
    • Google Scholar: 319
    • Scopus: 269
    • Web of Science: 250
    • ResearchGate: 269
  • H-index:
    • Google Scholar: 48
    • Scopus: 44
    • Web of Science: 44
    • ResearchGate: 43
  • i10-index: 176 (Google Scholar)

Teaching Courses:

  • General Chemistry, Aliphatic Organic Chemistry, Aromatic Organic Chemistry, Heterocyclic Chemistry, Functional Organic Chemistry, Physical Organic Chemistry, Biomolecules, Natural products, Organometallic Chemistry, Physical Pharmacy, Stereochemistry, Biochemistry, Advanced Heterocyclic Chemistry, Chemistry of Drugs, Green and Environmental Chemistry, Reactions and Mechanisms of Aliphatic Compounds, Spectroscopy (MS, IR, NMR, UV), Basic principles of Organic Chemistry for Pre-Pharmacy, Pre-Dental, Pre-Veterinary students, Practical Organic Chemistry for undergraduate students, Field Training, Graduation Project.

Professional Memberships and Achievements:

  • Scientific Societies:
    • Egyptian Society of Heterocyclic Chemistry (EHCS)
    • Performance appraisal and development committee (Cairo University)
    • Scientific culture committee (Cairo University)
    • Research Committee of the article and graduation projects (Cairo University)
    • Quality Committee, Department of Chemistry (Cairo University and Islamic University of Madinah)
    • Training and Development Committee, Faculty of Science, Islamic University of Madinah
    • Head of Chemistry Department, Faculty of Science, Islamic University of Madinah
    • Egyptian National Bioinformatics Network (BioNetMasr)
    • Scientific Research Deanship Council at the Islamic University
    • Sustainability Unit at the Islamic University
    • Supervised and launched academic programs and projects in Chemistry
    • Participated in numerous scientific and quality events

Conferences Attended:

  • Participated and presented in various international and national conferences, such as Biannual conference on chemistry (Cairo University), International conferences in Egypt, UAE, Morocco, and Saudi Arabia, Heterocyclic Chemistry meetings, Scientific Research Weeks, and Quality Weeks.

Experiences:

  • Proficient in PC software (ChemDraw, Excel, Word, PowerPoint)
  • Expertise in Mass Spectra, NMR, Organic Synthesis
  • Completed various training courses in IR, NMR, UV, GCMS, microanalytical instruments, effective presentation, new trends in teaching (E-Learning), effective teaching, credit hours education, scientific publications, utility of technology in teaching, and strategic planning.

Editorial and Reviewer Roles:

  • Editorial Board Member for 42 Journals: Including Molecules, Crystals, Scientific Reports, Mini-Reviews in Medicinal Chemistry, Current Medicinal Chemistry, and various other international journals.
  • Reviewer for 138 Journals: Including ACS Chemical Neuroscience, Acta Pharmaceutica Sinica B, Analytical Chemistry Letters, Anticancer Agents in Medicinal Chemistry, Arabian Journal of Chemistry, Bioorganic & Medicinal Chemistry Letters, European Journal of Medicinal Chemistry, Journal of Medicinal Chemistry, and many more.

Reviewing PhD Theses:

  • Reviewed several PhD theses on topics like environmental cost accounting, synthesis and biological evaluation of novel compounds, green chemistry methodologies, and heterocyclic ring synthesis.

Reviewing for Promotions:

  • Reviewed scientific production for the promotion of faculty members from various universities, including Imam Abdulrahman Bin Faisal University, University of Bisha, Northern Border University, Taibah University, Taif University, and Tabuk University.

Languages:

  • English (Good), French (Fair), German (Fair)

Supervision:

  • Supervisor for 17 MSc and 9 PhD theses.

Research Projects:

  • Engaged in multiple research projects funded by various institutions, focusing on green synthesis, characterization, biological evaluation of novel compounds, separation of rare earth elements, and innovative optical organic compounds for solar cells.

Awards and Recognition:

  • Best paper in heterocyclic chemistry from the Egyptian Heterocyclic Chemistry Society (E.H.C.S) for 2015.
  • Included in the list of the World’s Top 2% Scientists by Stanford University for the years 2019, 2020, and 2021.

Notable Publication:

Assoc Prof Dr. Zhijie Xu | Chemotherapy | Best Researcher Award

Assoc Prof Dr. Zhijie Xu | Chemotherapy | Best Researcher Award 

Xiangya Hospital Central South University | China

AUTHOR PROFILE

Scopus

Orcid ID

EARLY ACADEMIC PURSUITS

Zhijie Xu embarked on his academic journey with a solid foundation in medical laboratory science, earning his bachelor’s degree from Xiangya School of Medicine. His early interests focused on the mechanisms of disease at the cellular level, laying the groundwork for his future research endeavors.

PROFESSIONAL ENDEAVORS

Throughout his career, Zhijie Xu has held notable positions, including Associate Professor and Associate Chief Technician at Xiangya Hospital, Central South University. His professional roles have been complemented by his extensive involvement in editorial activities for prominent scientific journals, which underscores his influence in the field of oncology and pharmacology.

CONTRIBUTIONS AND RESEARCH FOCUS ON CHEMOTHERAPY

Zhijie Xu’s research has predominantly centered on the molecular and cellular mechanisms of cancer. His work has particularly focused on DNA-damage response, ubiquitination in human cancers, and cell autophagy related to radio-resistance in cancers. His contributions to understanding non-coding RNA and immunotherapy in lung cancers and gliomas are notable.

IMPACT AND INFLUENCE

With an H index of 30, Zhijie Xu’s research has had a significant impact on the scientific community. His findings have provided insights into the molecular underpinnings of cancer, influencing both basic and clinical cancer research. His editorial roles further amplify his influence, as he shapes the discourse in several high-impact journals.

ACADEMIC CITES

Zhijie Xu’s academic work is well-cited, reflecting the importance and relevance of his research. His contributions to understanding the complex mechanisms of cancer biology have been recognized and referenced by peers, solidifying his reputation in the scientific community.

LEGACY AND FUTURE CONTRIBUTIONS

Looking forward, Zhijie Xu aims to continue his groundbreaking research in cancer biology. His future work is expected to delve deeper into the mechanisms of cancer resistance and the development of novel therapeutic strategies. His ongoing projects and future initiatives are poised to further advance the field and contribute to the fight against cancer.

 

NOTABLE PUBLICATION:

Cancer Drugs and Vaccines

Cancer Drugs and Vaccines

Introduction: Cancer Drugs and Vaccines are at the forefront of oncology research and treatment, offering promising solutions in the fight against cancer. These innovative therapies aim to improve patient outcomes, enhance survival rates, and provide hope for individuals battling this devastating disease.

Subtopics in Cancer Drugs and Vaccines:

Immunotherapy in Cancer Treatment: Immunotherapy harnesses the power of the immune system to target and destroy cancer cells. Explore the latest developments in checkpoint inhibitors, CAR-T cell therapy, and immune checkpoint blockade.

Targeted Therapies: Targeted cancer drugs are designed to specifically target cancer cells with minimal damage to healthy tissues. Delve into the mechanisms and effectiveness of these precision therapies.

Vaccine-Based Approaches: Investigate the role of cancer vaccines in preventing or treating various types of cancer. Discover the development and clinical trials of vaccines that stimulate the immune system to recognize and combat cancer cells.

Combination Therapies: Combinatorial approaches involving a mix of drugs, vaccines, and other treatments are gaining traction. Explore how these synergistic combinations are revolutionizing cancer care.

Personalized Medicine: Learn about the concept of tailoring cancer treatments to individual patients based on their genetic and molecular profiles. Explore the advancements in genomic medicine and its impact on cancer drug development.

Resistance Mechanisms: Understand the challenges posed by drug resistance in cancer treatment and how researchers are addressing these issues through innovative strategies.

Emerging Biomarkers: Discover the latest biomarkers used in cancer diagnosis, prognosis, and treatment selection, paving the way for more personalized and effective therapies.

Clinical Trials and Regulatory Challenges: Examine the critical role of clinical trials in evaluating the safety and efficacy of cancer drugs and vaccines, along with the regulatory processes that govern their approval.

Future Trends in Cancer Therapeutics: Explore the cutting-edge technologies and trends shaping the future of cancer treatment, from nanomedicine to gene editing and beyond.

Patient Perspectives and Support: Consider the holistic approach to cancer care, including patient support systems, psychosocial aspects, and quality of life improvements alongside drug and vaccine development.