Serine Metabolic Plasticity Empowers Pancreatic Cancer Resilience| #pencis #researcherawards
Pancreatic cancer is one of the most lethal malignancies, notorious ...
Pancreatic cancer is one of the most lethal malignancies, notorious for its adaptive resistance to treatment and poor prognosis. Recent research has highlighted a fascinating and crucial survival mechanism—serine-driven metabolic ...plasticity—which enables pancreatic cancer cells to dynamically shift their metabolic pathways in response to environmental stress. This metabolic reprogramming allows cancer cells to survive nutrient scarcity, hypoxia, and chemotherapeutic interventions. Serine, a non-essential amino acid, plays a pivotal role in supporting nucleotide biosynthesis, redox balance, and one-carbon metabolism, making it central to tumor growth and survival.
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#SerineMetabolism, #PancreaticCancer, #CancerAdaptation, #TumorPlasticity, #MetabolicResilience, #AminoAcidPathways, #CancerResearch, #RedoxBalance, #TherapeuticTargets, #ChemoResistance, #OneCarbonMetabolism, #TumorSurvival, #Bioenergetics, #MetabolicFlexibility, #PrecisionOncology, #CancerTherapy, #TumorMicroenvironment, #SyntheticLethality, #MetabolicRewiring, #OncologyUpdates, #CancerBreakthroughs, #Metabolomics, #OncoTargets, #PencisOncology, #OncologyAwards,Show More