Role of EZH2 in bone marrow mesenchymal stem cells and immune–cancer interactions.

EZH2 (Enhancer of Zeste Homolog 2) is a key epigenetic enzyme that modifies chromatin to silence specific genes. In bone marrow mesenchymal stem cells, EZH2 regulates cell differentiation, immune modulation, ...and secretion of signaling molecules. Abnormal EZH2 activity can remodel the bone marrow microenvironment to favor cancer cell survival, metastasis, and immune suppression. By influencing interactions between immune cells and cancer cells, EZH2 contributes to tumor progression and therapy resistance. Targeting EZH2 may therefore improve anti-cancer immune responses and represent a promising therapeutic strategy in bone-related and hematologic malignancies.

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Role of EZH2 in bone marrow mesenchymal stem cells and immune–cancer interactions.
Role of EZH2 in bone marrow mesenchymal stem cells and immune–cancer interactions.
EZH2 (Enhancer of Zeste Homolog 2) is a key epigenetic enzyme that ...
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