Mr. Shijia Lu | Medicine | Best Researcher Award

Sanquan College of Xinxiang Medical University | China

AUTHOR PROFILE

ORCID ID

🏥MR. SHIJIA LU: ACADEMIC AND PROFESSIONAL PROFILE

🎓EARLY ACADEMIC PURSUITS

Mr. Shijia Lu embarked on his academic journey with a Bachelor’s degree in Biotechnology from Sanquan College of Xinxiang Medical University. Demonstrating early interest in tumor-targeted therapy, he quickly advanced into translational research and academic publishing. His undergraduate years were marked by robust interdisciplinary learning, laying the foundation for integrating bioinformatics, network pharmacology, and molecular simulations in cancer research.

🩺PROFESSIONAL ENDEAVORS

Currently serving as the Associate Editor of Guide to Biomedical Research Tools, Mr. Lu also holds student membership in the Chinese Society for Biotechnology. His roles extend beyond editorial to include project leadership, drug discovery, and computational biology. He has successfully led and contributed to university-level and provincial scientific projects, focusing on innovative strategies to combat cancer resistance.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON MEDICINE

Mr. Lu’s research is centered on tumor-targeted therapies, especially those overcoming PCNA-mediated resistance. Notable among his contributions:

  • Invented the “Structural Coupling – Functional Synergy” strategy, bridging natural product EGCG and synthetic inhibitors for synergistic effects.

  • Designed AL-1/AL-3, novel dual-ligand inhibitors tackling L47V mutation resistance in cancer cells.

  • Engaged in multi-omics-driven screening for anti-cancer components in natural sources such as pomegranate peel.
    His integrative research style blends wet-lab validation with computational simulations (AutoDock Vina, Cytoscape, ESM-Fold), setting a new paradigm in anti-cancer drug design.

🌍IMPACT AND INFLUENCE

Lu’s research has received national-level recognition, influencing the development of next-generation PCNA inhibitors. His PCNA-targeted strategy, featured in In Silico Research in Biomedicine, provides a blueprint for multi-target drug designs. Through editorial and competition platforms, he has advocated bioinformatics integration in biomedical research, inspiring peer groups and junior researchers in China’s academic circuits.

🏆 ACCOLADES AND RECOGNITION

Awards:
🥈 Second Prize, National College Students’ Innovation and Entrepreneurship Competition (Medical Health Category)
🏅 Three national-level research competition awards
🌍 Two provincial-level foreign language translation awards

🏆LEGACY AND FUTURE CONTRIBUTIONS

Mr. Lu’s pioneering research in drug resistance mechanisms, particularly in PCNA-targeted therapy, promises long-term value to precision oncology. His interdisciplinary approach—linking structural biology, network pharmacology, and bioinformatics—will likely influence future drug discovery pipelines, especially for hard-to-treat tumors. He is poised to emerge as a thought leader in the next generation of biomedical researchers.

🧬CONCLUSION

With a dynamic blend of technical mastery, scientific curiosity, and a vision for impact, Mr. Shijia Lu is a rising biomedical innovator. His work addresses one of the greatest challenges in medicine today—anti-cancer drug resistance—while his leadership in academia and publishing continues to foster new frontiers in biotechnology and translational research.

📊🔬NOTABLE PUBLICATION:

Design and anti-drug resistance research of novel PCNA-targeted inhibitors based on network pharmacology and molecular docking

Authors: Shijia Lu; YiRan Zhen; Jinwen Sima; Jinle Wang; Qihao Zhu; Miaoyan Han; Mengdan Sang; Xuejiao Li; Bing Zhang; Zihan Wang; et al.

Journal: In Silico Research in Biomedicine

Year: 2025

Shijia Lu | Medicine | Best Researcher Award