Ms. Xi Chen | Preimplantation Genetic Testing | Best Researcher Award

Peking University Third Hospital | China

AUTHOR PROFILE

SCOPUS ID

🏥MS. XI CHEN: ACADEMIC AND PROFESSIONAL PROFILE

🎓EARLY ACADEMIC PURSUITS

Ms. Xi Chen embarked on her academic journey at Shandong University, where she earned a Bachelor’s degree in Clinical Medicine, laying a strong foundation in clinical sciences. Her commitment to women’s health and reproductive medicine led her to pursue a Ph.D. in Obstetrics and Gynecology at Peking University, one of China’s premier medical institutions.

🩺PROFESSIONAL ENDEAVORS

Ms. Chen has consistently demonstrated excellence in both academic and clinical settings. As a Licensed Physician in China, she bridges research and clinical application, ensuring her work has tangible impact on patient care. Her academic training has been complemented by significant research experience, especially in the field of reproductive genetics.

🔬CONTRIBUTIONS AND RESEARCH FOCUS ON PREIMPLANTATION GENETIC TESTING(PGT)

Ms. Chen’s research primarily explores the genetic etiology of adverse pregnancy outcomes, with a special emphasis on Preimplantation Genetic Testing for Monogenic diseases (PGT-M). Her major contributions include:

  1. Investigation of genetic causes of recurrent fetal anomalies, especially those unexplained by traditional diagnostics.

  2. Application of PGT-M in hereditary tumor syndromes, even in cases without a known family history—enhancing the scope and sensitivity of reproductive genetic screening.

  3. Exploring key gene functions in blastocyst development and implantation, bridging the gap between molecular genetics and clinical reproductive outcomes.

🌍IMPACT AND INFLUENCE

Ms. Chen’s work has contributed to advancing precision reproductive medicine in China and beyond. Her research on using affected embryos or single sperm for linkage analysis in PGT-M has opened new avenues for patients with hereditary tumors lacking family history—setting new standards for ethical and practical approaches in assisted reproduction.

🏆ACCOLADES AND RECOGNITION

  • Outstanding Student Cadre, Peking University

  • National Second-Class Academic Scholarship

  • Outstanding Individual in Summer Social Practice, Peking University

These honors reflect her academic excellence, leadership qualities, and community engagement.

🏆LEGACY AND FUTURE CONTRIBUTIONS

Ms. Chen is poised to become a leading figure in reproductive genetics, particularly in the ethical expansion and technical innovation of PGT-M. Her dedication to unraveling complex genetic causes of adverse pregnancy is expected to revolutionize the early detection and prevention of hereditary diseases.

🧬CONCLUSION

Ms. Xi Chen stands at the forefront of reproductive genetics research. With a rare combination of clinical experience, scientific rigor, and innovative thinking, she continues to shape the future of personalized reproductive healthcare. Her commitment to improving diagnostic and therapeutic outcomes for families affected by genetic disorders is both admirable and impactful.

📊🔬NOTABLE PUBLICATION:

Application of the PGT-M strategy using single sperm and/or affected embryos as probands for linkage analysis in males with hereditary tumor syndromes without family history

  • Authors: Chen X#, Wang Y, Guan S, Yan Z, Zhu X, Kuo Y, Wang N, Zhi X, Lian Y, Huang J, Liu P, Li R, Yan L, Qiao J
  • Journal: Journal of Human Genetics
  • Year: 2023 (Published August 18)

Functional profiling of stage-specific proteome and translational transition across human pre-implantation embryo development at a single-cell resolution

  • Dang Y#, Zhu L#, Yuan P#, Liu Q#, Guo Q, Chen X, Gao S, Liu X, Ji S, Yuan Y, Lian Y, Li R, Yan L*, Wong C*, Qiao J*
  • Journal: Cell Discovery
  • Year: 2023

Advances in studying human gametogenesis and embryonic development in China

  • Authors: Liu Q#, Chen X#, Qiao J
  • Journal: Biology of Reproduction
  • Year: 2022
Xi Chen | Preimplantation Genetic Testing | Best Researcher Award