Dr. Wenjin Wang | Targeted Cancer Therapy | Young Scientist Award

The Chinese University of Hong Kong | China

Author Profile

Scopus

Dr. Wenjin Wang 🌟🔬

Postdoctoral Researcher | Tumor Photodynamic Therapy Expert | Biomolecular Phase Separation Investigator

Research Interests

1. Tumor Photodynamic Therapy (PDT) 💡🎯
   • Design and synthesis of novel photosensitizers for PDT.
   • Development of tumor-targeted PDT using tumor-responsive AIE (Aggregation-Induced Emission) photosensitizers.
2. Regulation of Biomolecular Phase Separation 🧬⚛️
   • Investigation into the phase separation behaviors of biomolecules like proteins and nucleic acids.
   • Modulation of these processes with chemical molecules to enhance understanding of intracellular organization and function.

Professional Experience

• Postdoctoral Researcher 🏢
  The Chinese University of Hong Kong, Shenzhen (07/2022–Present)
  • Research on bioapplications of AIE materials under Prof. Ben Zhong Tang.
• Biochemical Engineer 🧪
  Shenzhen BGI Research Institute (10/2017–09/2018)
  • Designed and optimized unnatural nucleotides for sequencing applications.
• Laboratory Assistant 🔬
  Peking University Shenzhen Graduate School (11/2016–10/2017)
  • Focused on unnatural amino acids and asymmetric carbene O-H bond insertion catalysis by myoglobin proteins.
• Research Associate 💊
  Tianjin Institute of Pharmaceutical Research (08/2014–11/2016)
  • Developed new hypoglycemic drugs through innovative designs and research.

Education

• Ph.D. in Chemical Biology 🧫
  Sun Yat-Sen University (09/2018–06/2022)
  • Thesis: Antitumor mechanisms of metal complexes and their regulation on biomolecular phase separation behavior.
• M.S. in Pharmacy 💊
  Tianjin Medical University (09/2012–06/2015)
  • Research: Development of SGLT2 inhibitors and hypoglycemic activity evaluation.
• B.S. in Pharmacy 🏥
  Tianjin Medical University (09/2008–06/2012)

Grants and Funding 💰📚

1. National Natural Science Foundation of China
   • Ruthenium Complexes and Lipid Phase Separation in Antitumor Research (2024–2026, RMB 300K, Principal Investigator).
2. China Postdoctoral Science Foundation
   • GGT-Activated AIE Photosensitizers for Tumor Photodynamic Therapy (2022–2025, RMB 80K, Principal Investigator).
3. Shenzhen Medical Research Fund
   • Manipulable Aggregation of AIE Photosensitizers for Enhanced Tumor PDT (2025–2027, RMB 800K, Principal Investigator).
4. National Natural Science Foundation of China
   • Phase Separation Mechanism of Antitumor Phosphor Metal Complexes (2022–2025, RMB 630K, Major Participant).
5. Yunnan Province Science and Technology Plan
   • Aggregate Induced Luminescence in Biomass Resources (2024–2026, RMB 2000K, Major Participant).

Awards and Honors 🏆✨

• Excellent Postdoctoral Doctor (Shenzhen, 12/2023).
• National Scholarship for Doctoral Students (12/2021).
• “Fran” Excellent Thesis Scholarship (Second Class, Sun Yat-sen University, 11/2021).
• Excellent Wall Poster Award (32nd Academic Annual Meeting, Chinese Chemical Society, 04/2021).

Key Contributions 📈

Dr. Wang’s groundbreaking research combines innovative photodynamic therapies and the manipulation of biomolecular phase separation, driving advancements in cancer treatment and molecular biology.